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Single Molecule FRET Analysis of CRISPR Cas9 Single Guide RNA Folding Dynamics
[Image: see text] CRISPR Cas9 is an RNA guided endonuclease that is part of a bacterial adaptive immune system. Single guide RNA (sgRNA) can be designed to target genomic DNA, making Cas9 a programmable DNA binding/cutting enzyme and allowing applications such as epigenome editing, controlling trans...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841515/ https://www.ncbi.nlm.nih.gov/pubmed/36563314 http://dx.doi.org/10.1021/acs.jpcb.2c05428 |