Disparate Regions of the Human Chemokine CXCL10 Exhibit Broad-Spectrum Antimicrobial Activity against Biodefense and Antibiotic-Resistant Bacterial Pathogens

[Image: see text] CXCL10 is a pro-inflammatory chemokine produced by the host in response to microbial infection. In addition to canonical, receptor-dependent actions affecting immune-cell migration and activation, CXCL10 has also been found to directly kill a broad range of pathogenic bacteria. Pri...

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Detalles Bibliográficos
Autores principales: Crawford, Matthew A., Ward, Amanda E., Gray, Vincent, Bailer, Peter, Fisher, Debra J., Kubicka, Ewa, Cui, Zixian, Luo, Qinmo, Gray, Mary C., Criss, Alison K., Lum, Lawrence G., Tamm, Lukas K., Letteri, Rachel A., Hughes, Molly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841529/
https://www.ncbi.nlm.nih.gov/pubmed/36475632
http://dx.doi.org/10.1021/acsinfecdis.2c00456

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