Thienopyrimidine Derivatives as GPR55 Receptor Antagonists: Insight into Structure–Activity Relationship

[Image: see text] GPR55 is an orphan G-protein coupled receptor involved in various pathophysiological conditions. However, there are only a few noncannabinoid GPR55 ligands reported so far. The lack of potent and selective GPR55 ligands precludes a deep exploration of this receptor. The studies pre...

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Detalles Bibliográficos
Autores principales: Figuerola-Asencio, Laura, Morales, Paula, Zhao, Pingwei, Hurst, Dow P., Sayed, Sommayah S., Colón, Katsuya L., Gómez-Cañas, María, Fernández-Ruiz, Javier, Croatt, Mitchell P., Reggio, Patricia H., Abood, Mary E., Jagerovic, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841585/
https://www.ncbi.nlm.nih.gov/pubmed/36655130
http://dx.doi.org/10.1021/acsmedchemlett.2c00325

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