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Phosphorylation of TGIF2 represents a therapeutic target that drives EMT and metastasis of lung adenocarcinoma

BACKGROUND: TGF-β-induced factor homeobox 2 (TGIF2) is a transcription regulator that is phosphorylated by EGFR/ERK signaling. However, the functions of phosphorylated (p)-TGIF2 in cancer are largely unknown. Here, we investigated the roles of p-TGIF2 in promoting epithelial–mesenchymal transition (...

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Detalles Bibliográficos
Autores principales:	Du, Renle, Wang, Chen, Liu, Jingjing, Wang, Keyan, Dai, Liping, Shen, Wenzhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841675/ https://www.ncbi.nlm.nih.gov/pubmed/36647029 http://dx.doi.org/10.1186/s12885-023-10535-9

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