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Physical Activity, Sedentary Behavior, and Risk of Coronavirus Disease 2019

INTRODUCTION: Data on the associations of prepandemic physical activity and sedentary behavior with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) severity, particularly milder illness, have been limited. METHODS: We used data from 43,9...

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Autores principales: Ma, Wenjie, Murray, Erin, Nguyen, Long H., Drew, David A., Ding, Ming, Stopsack, Konrad H., Rich-Edwards, Janet W., Hart, Jaime E., Figueiredo, Jane C., Lacey, James V., Patel, Alpa V., Bhupathiraju, Shilpa N., Chan, Andrew T., Martinez, Maria Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842390/
https://www.ncbi.nlm.nih.gov/pubmed/36657558
http://dx.doi.org/10.1016/j.amjmed.2022.12.029
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author Ma, Wenjie
Murray, Erin
Nguyen, Long H.
Drew, David A.
Ding, Ming
Stopsack, Konrad H.
Rich-Edwards, Janet W.
Hart, Jaime E.
Figueiredo, Jane C.
Lacey, James V.
Patel, Alpa V.
Bhupathiraju, Shilpa N.
Chan, Andrew T.
Martinez, Maria Elena
author_facet Ma, Wenjie
Murray, Erin
Nguyen, Long H.
Drew, David A.
Ding, Ming
Stopsack, Konrad H.
Rich-Edwards, Janet W.
Hart, Jaime E.
Figueiredo, Jane C.
Lacey, James V.
Patel, Alpa V.
Bhupathiraju, Shilpa N.
Chan, Andrew T.
Martinez, Maria Elena
author_sort Ma, Wenjie
collection PubMed
description INTRODUCTION: Data on the associations of prepandemic physical activity and sedentary behavior with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) severity, particularly milder illness, have been limited. METHODS: We used data from 43,913 participants within the Nurses’ Health Study II and Health Professionals Follow-Up Study who responded to periodic COVID-related surveys from May 2020 through March 2021. History of physical activity from the prepandemic period was assessed as the metabolic equivalents of task (MET)-hours per week of various activities of different intensity and sedentary behavior assessed from reports of time spent sitting from questionnaires completed 2016-2017. Multivariable logistic regression models were fitted to calculate the odds ratios (ORs) and 95% confidence intervals (CIs) for risk of SARS-CoV-2 infection and COVID-19 severity, as well as predicted COVID-19 defined using a validated symptom-based algorithm. RESULTS: Higher levels of prepandemic physical activity were associated with a lower risk for SARS-CoV-2 infection. Compared to participants with <3 MET-hours per week, the multivariable-adjusted OR was 0.86 (95% CI: 0.74, 0.99; P trend =.07) for those with ≥27 MET-hours per week. Higher physical activity levels were also associated with lower risk of symptomatic SARS-CoV-2 infection (OR: 0.84; 95% CI: 0.72, 0.99; P trend = .05) and predicted COVID-19 (OR: 0.87; 95% CI: 0.78, 0.97; P trend = .01). Longer time sitting at home watching TV (OR: 0.85; 95% CI: 0.73, 0.97) or for other tasks (OR: 0.78; 95% CI: 0.66, 0.92) was associated with a lower risk of SARS-CoV-2 infection. CONCLUSIONS: Our findings support a protective association between prepandemic physical activity and lower risk and severity of COVID-19.
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spelling pubmed-98423902023-01-17 Physical Activity, Sedentary Behavior, and Risk of Coronavirus Disease 2019 Ma, Wenjie Murray, Erin Nguyen, Long H. Drew, David A. Ding, Ming Stopsack, Konrad H. Rich-Edwards, Janet W. Hart, Jaime E. Figueiredo, Jane C. Lacey, James V. Patel, Alpa V. Bhupathiraju, Shilpa N. Chan, Andrew T. Martinez, Maria Elena Am J Med Clinical Research Study INTRODUCTION: Data on the associations of prepandemic physical activity and sedentary behavior with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) severity, particularly milder illness, have been limited. METHODS: We used data from 43,913 participants within the Nurses’ Health Study II and Health Professionals Follow-Up Study who responded to periodic COVID-related surveys from May 2020 through March 2021. History of physical activity from the prepandemic period was assessed as the metabolic equivalents of task (MET)-hours per week of various activities of different intensity and sedentary behavior assessed from reports of time spent sitting from questionnaires completed 2016-2017. Multivariable logistic regression models were fitted to calculate the odds ratios (ORs) and 95% confidence intervals (CIs) for risk of SARS-CoV-2 infection and COVID-19 severity, as well as predicted COVID-19 defined using a validated symptom-based algorithm. RESULTS: Higher levels of prepandemic physical activity were associated with a lower risk for SARS-CoV-2 infection. Compared to participants with <3 MET-hours per week, the multivariable-adjusted OR was 0.86 (95% CI: 0.74, 0.99; P trend =.07) for those with ≥27 MET-hours per week. Higher physical activity levels were also associated with lower risk of symptomatic SARS-CoV-2 infection (OR: 0.84; 95% CI: 0.72, 0.99; P trend = .05) and predicted COVID-19 (OR: 0.87; 95% CI: 0.78, 0.97; P trend = .01). Longer time sitting at home watching TV (OR: 0.85; 95% CI: 0.73, 0.97) or for other tasks (OR: 0.78; 95% CI: 0.66, 0.92) was associated with a lower risk of SARS-CoV-2 infection. CONCLUSIONS: Our findings support a protective association between prepandemic physical activity and lower risk and severity of COVID-19. Elsevier Inc. 2023-06 2023-01-16 /pmc/articles/PMC9842390/ /pubmed/36657558 http://dx.doi.org/10.1016/j.amjmed.2022.12.029 Text en © 2023 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Clinical Research Study
Ma, Wenjie
Murray, Erin
Nguyen, Long H.
Drew, David A.
Ding, Ming
Stopsack, Konrad H.
Rich-Edwards, Janet W.
Hart, Jaime E.
Figueiredo, Jane C.
Lacey, James V.
Patel, Alpa V.
Bhupathiraju, Shilpa N.
Chan, Andrew T.
Martinez, Maria Elena
Physical Activity, Sedentary Behavior, and Risk of Coronavirus Disease 2019
title Physical Activity, Sedentary Behavior, and Risk of Coronavirus Disease 2019
title_full Physical Activity, Sedentary Behavior, and Risk of Coronavirus Disease 2019
title_fullStr Physical Activity, Sedentary Behavior, and Risk of Coronavirus Disease 2019
title_full_unstemmed Physical Activity, Sedentary Behavior, and Risk of Coronavirus Disease 2019
title_short Physical Activity, Sedentary Behavior, and Risk of Coronavirus Disease 2019
title_sort physical activity, sedentary behavior, and risk of coronavirus disease 2019
topic Clinical Research Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842390/
https://www.ncbi.nlm.nih.gov/pubmed/36657558
http://dx.doi.org/10.1016/j.amjmed.2022.12.029
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