CDK5RAP3 acts as a tumour suppressor in gastric cancer through the infiltration and polarization of tumour-associated macrophages

We have demonstrated that CDK5RAP3 exerts a tumour suppressor effect in gastric cancer, but its role in regulating tumour-associated macrophages (TAMs) has not yet been reported. Here, we show that CDK5RAP3 is related to the infiltration and polarization of macrophages. It inhibits the polarization...

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Detalles Bibliográficos
Autores principales: Wang, Jia-Bin, Gao, You-Xin, Ye, Yin-Hua, Lin, Tong-Xing, Li, Ping, Lin, Jian-Xian, Chen, Qi-Yue, Cao, Long-Long, Lin, Mi, Tu, Ru-Hong, Lin, Ju-Li, Huang, Ze-Ning, Zheng, Hua-Long, Xie, Jian-Wei, Zheng, Chao-Hui, Huang, Chang-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842504/
https://www.ncbi.nlm.nih.gov/pubmed/35999359
http://dx.doi.org/10.1038/s41417-022-00515-9

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