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Polygenic risk score for tumor aggressiveness and early-onset prostate cancer in Asians

We attempted to assess the performance of an ethnic-specific polygenic risk score (PRS) designed from a Korean population to predict aggressive prostate cancer (PCa) and early-onset (age < 60). A PRS score comprised of 22 SNPs was computed in 3695 patients gathered from one of 4 tertiary centers...

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Detalles Bibliográficos
Autores principales: Song, Sang Hun, Kim, Eunae, Jung, Yu Jin, Kim, Hak-Min, Park, Moon Soo, Kim, Jung Kwon, Lee, Hakmin, Oh, Jong Jin, Lee, Sangchul, Hong, Sung Kyu, Byun, Seok-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842611/
https://www.ncbi.nlm.nih.gov/pubmed/36646726
http://dx.doi.org/10.1038/s41598-022-17515-2