Lineage-specific regulatory changes in hypertrophic cardiomyopathy unraveled by single-nucleus RNA-seq and spatial transcriptomics

Hypertrophic cardiomyopathy (HCM) is the most common cardiac genetic disorder characterized by cardiomyocyte hypertrophy and cardiac fibrosis. Pathological cardiac remodeling in the myocardium of HCM patients may progress to heart failure. An in-depth elucidation of the lineage-specific changes in p...

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Detalles Bibliográficos
Autores principales: Liu, Xuanyu, Yin, Kunlun, Chen, Liang, Chen, Wen, Li, Wenke, Zhang, Taojun, Sun, Yang, Yuan, Meng, Wang, Hongyue, Song, Yunhu, Wang, Shuiyun, Hu, Shengshou, Zhou, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842679/
https://www.ncbi.nlm.nih.gov/pubmed/36646705
http://dx.doi.org/10.1038/s41421-022-00490-3

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