Machine learning and metabolic modelling assisted implementation of a novel process analytical technology in cell and gene therapy manufacturing

Process analytical technology (PAT) has demonstrated huge potential to enable the development of improved biopharmaceutical manufacturing processes by ensuring the reliable provision of quality products. However, the complexities associated with the manufacture of advanced therapy medicinal products...

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Detalles Bibliográficos
Autores principales: Williams, Thomas, Kalinka, Kevin, Sanches, Rui, Blanchard-Emmerson, Greg, Watts, Samuel, Davies, Lee, Knevelman, Carol, McCloskey, Laura, Jones, Peter, Mitrophanous, Kyriacos, Miskin, James, Dikicioglu, Duygu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842697/
https://www.ncbi.nlm.nih.gov/pubmed/36646795
http://dx.doi.org/10.1038/s41598-023-27998-2

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