Niche stiffness sustains cancer stemness via TAZ and NANOG phase separation

Emerging evidence shows that the biomechanical environment is required to support cancer stem cells (CSCs), which play a crucial role in drug resistance. However, how mechanotransduction signals regulate CSCs and its clinical significance has remained unclear. Using clinical-practice ultrasound elas...

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Detalles Bibliográficos
Autores principales: Liu, Xinwei, Ye, Yingying, Zhu, Liling, Xiao, Xiaoyun, Zhou, Boxuan, Gu, Yuanting, Si, Hang, Liang, Huixin, Liu, Mingzhu, Li, Jiaqian, Jiang, Qiongchao, Li, Jiang, Yu, Shubin, Ma, Ruiying, Su, Shicheng, Liao, Jian-You, Zhao, Qiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842735/
https://www.ncbi.nlm.nih.gov/pubmed/36646707
http://dx.doi.org/10.1038/s41467-023-35856-y

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