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The telomerase activator TA-65 protects from cigarette smoke-induced small airway remodeling in mice through extra-telomeric effects

Small airway remodeling (SAR) is a key phenomenon of airflow obstruction in smokers, leading to chronic obstructive pulmonary disease (COPD). SAR results in an increased thickness of small airway walls, with a combination of peribronchiolar fibrosis with increased fibrous tissue and accumulation of...

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Detalles Bibliográficos
Autores principales: Tiendrébéogo, Arnaud Jean Florent, Soumagne, Thibaud, Pellegrin, François, Dagouassat, Maylis, Tran Van Nhieu, Jeanne, Caramelle, Philippe, Paul, Emmanuel N., Even, Benjamin, Zysman, Maeva, Julé, Yvon, Samb, Abdoulaye, Boczkowski, Jorge, Lanone, Sophie, Schlemmer, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842758/
https://www.ncbi.nlm.nih.gov/pubmed/36646720
http://dx.doi.org/10.1038/s41598-022-25993-7