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Synovial sarcoma of the vulva: A case report and literature review with discussion on fertility sparing approaches

• Vulvar synovial sarcoma is a rare malignancy with unclear treatment guidelines but usually includes surgical resection. • Our literature review demonstrates additional survival benefit from addition of radiotherapy to surgical resection. • There is no specific guidance in the literature for the ad...

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Autores principales: Schoettle, Gabriella, Gulstene, Stephanie, Vickress, Jason, Sugimoto, Akira, D'Souza, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842853/
https://www.ncbi.nlm.nih.gov/pubmed/36659908
http://dx.doi.org/10.1016/j.gore.2023.101132
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author Schoettle, Gabriella
Gulstene, Stephanie
Vickress, Jason
Sugimoto, Akira
D'Souza, David
author_facet Schoettle, Gabriella
Gulstene, Stephanie
Vickress, Jason
Sugimoto, Akira
D'Souza, David
author_sort Schoettle, Gabriella
collection PubMed
description • Vulvar synovial sarcoma is a rare malignancy with unclear treatment guidelines but usually includes surgical resection. • Our literature review demonstrates additional survival benefit from addition of radiotherapy to surgical resection. • There is no specific guidance in the literature for the addition of systemic agents to treat vulvovaginal disease. • Our patient received wide surgical excision and IMRT radiotherapy with no signs of recurrence 2 years from treatment. • She conceived after treatment. This has only been documented once before with different, less accessible treatments.
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spelling pubmed-98428532023-01-18 Synovial sarcoma of the vulva: A case report and literature review with discussion on fertility sparing approaches Schoettle, Gabriella Gulstene, Stephanie Vickress, Jason Sugimoto, Akira D'Souza, David Gynecol Oncol Rep Case Report • Vulvar synovial sarcoma is a rare malignancy with unclear treatment guidelines but usually includes surgical resection. • Our literature review demonstrates additional survival benefit from addition of radiotherapy to surgical resection. • There is no specific guidance in the literature for the addition of systemic agents to treat vulvovaginal disease. • Our patient received wide surgical excision and IMRT radiotherapy with no signs of recurrence 2 years from treatment. • She conceived after treatment. This has only been documented once before with different, less accessible treatments. Elsevier 2023-01-08 /pmc/articles/PMC9842853/ /pubmed/36659908 http://dx.doi.org/10.1016/j.gore.2023.101132 Text en © 2023 Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Schoettle, Gabriella
Gulstene, Stephanie
Vickress, Jason
Sugimoto, Akira
D'Souza, David
Synovial sarcoma of the vulva: A case report and literature review with discussion on fertility sparing approaches
title Synovial sarcoma of the vulva: A case report and literature review with discussion on fertility sparing approaches
title_full Synovial sarcoma of the vulva: A case report and literature review with discussion on fertility sparing approaches
title_fullStr Synovial sarcoma of the vulva: A case report and literature review with discussion on fertility sparing approaches
title_full_unstemmed Synovial sarcoma of the vulva: A case report and literature review with discussion on fertility sparing approaches
title_short Synovial sarcoma of the vulva: A case report and literature review with discussion on fertility sparing approaches
title_sort synovial sarcoma of the vulva: a case report and literature review with discussion on fertility sparing approaches
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842853/
https://www.ncbi.nlm.nih.gov/pubmed/36659908
http://dx.doi.org/10.1016/j.gore.2023.101132
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