Cargando…
AMPK integrates metabolite and kinase-based immunometabolic control in macrophages
OBJECTIVE: Previous mechanistic studies on immunometabolism have focused on metabolite-based paradigms of regulation, such as itaconate. Here, we, demonstrate integration of metabolite and kinase-based immunometabolic control by AMP kinase. METHODS: We combined whole cell quantitative proteomics wit...
Autores principales: | Phair, Iain R., Nisr, Raid B., Howden, Andrew J.M., Sovakova, Magdalena, Alqurashi, Noor, Foretz, Marc, Lamont, Douglas, Viollet, Benoit, Rena, Graham |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842865/ https://www.ncbi.nlm.nih.gov/pubmed/36586434 http://dx.doi.org/10.1016/j.molmet.2022.101661 |
Ejemplares similares
-
Amino acid homeostasis is a target of metformin therapy
por: Forteath, Calum, et al.
Publicado: (2023) -
Activation of AMPK for a Break in Hepatic Lipid Accumulation and Circulating Cholesterol
por: Foretz, Marc, et al.
Publicado: (2018) -
AMPK Activation Reduces Hepatic Lipid Content by Increasing Fat Oxidation In Vivo
por: Foretz, Marc, et al.
Publicado: (2018) -
AMPK is not required for the effect of metformin on the inhibition of BMP6-induced hepcidin gene expression in hepatocytes
por: Deschemin, Jean-Christophe, et al.
Publicado: (2017) -
Obesity Impairs Skeletal Muscle Regeneration Through Inhibition of AMPK
por: Fu, Xing, et al.
Publicado: (2016)