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A phosphorylation switch controls androgen biosynthesis in prostate cancer

Androgen biosynthesis enzyme 3β-hydroxysteroid dehydrogenase type 1 (3βHSD1) encoded by HSD3B1 has emerged as a potential driver for therapeutic resistance in prostate cancer. Patients with homozygous HSD3B1(1245C) inheritance are intrinsically more resistant to currently available androgen/androgen...

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Detalles Bibliográficos
Autor principal:	Qiu, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843042/ https://www.ncbi.nlm.nih.gov/pubmed/36647834 http://dx.doi.org/10.1172/JCI166499

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