Karyopherin α deficiency contributes to human preimplantation embryo arrest

Preimplantation embryo arrest (PREMBA) is a common cause of female infertility and recurrent failure of assisted reproductive technology. However, the genetic basis of PREMBA is largely unrevealed. Here, using whole-exome sequencing data from 606 women experiencing PREMBA compared with 2,813 control...

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Detalles Bibliográficos
Autores principales: Wang, Wenjing, Miyamoto, Yoichi, Chen, Biaobang, Shi, Juanzi, Diao, Feiyang, Zheng, Wei, Li, Qun, Yu, Lan, Li, Lin, Xu, Yao, Wu, Ling, Mao, Xiaoyan, Fu, Jing, Li, Bin, Yan, Zheng, Shi, Rong, Xue, Xia, Mu, Jian, Zhang, Zhihua, Wu, Tianyu, Zhao, Lin, Wang, Weijie, Zhou, Zhou, Dong, Jie, Li, Qiaoli, Jin, Li, He, Lin, Sun, Xiaoxi, Lin, Ge, Kuang, Yanping, Wang, Lei, Sang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843055/
https://www.ncbi.nlm.nih.gov/pubmed/36647821
http://dx.doi.org/10.1172/JCI159951

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