Immunotherapy-induced neutralizing antibodies disrupt allergen binding and sustain allergen tolerance in peanut allergy

In IgE-mediated food allergies, exposure to the allergen activates systemic allergic responses. Oral immunotherapy (OIT) treats food allergies through incremental increases in oral allergen exposure. However, OIT only induces sustained clinical tolerance and decreased basophil sensitivity in a subse...

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Detalles Bibliográficos
Autores principales: LaHood, Nicole A., Min, Jungki, Keswani, Tarun, Richardson, Crystal M., Amoako, Kwasi, Zhou, Jingjia, Marini-Rapoport, Orlee, Bernard, Hervé, Hazebrouck, Stéphane, Shreffler, Wayne G., Love, J. Christopher, Pomes, Anna, Pedersen, Lars C., Mueller, Geoffrey A., Patil, Sarita U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843057/
https://www.ncbi.nlm.nih.gov/pubmed/36647835
http://dx.doi.org/10.1172/JCI164501

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