Features of tumor-microenvironment images predict targeted therapy survival benefit in patients with EGFR-mutant lung cancer

Tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR) are effective for many patients with lung cancer with EGFR mutations. However, not all patients are responsive to EGFR TKIs, including even those harboring EGFR-sensitizing mutations. In this study, we quantified the...

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Detalles Bibliográficos
Autores principales: Wang, Shidan, Rong, Ruichen, Yang, Donghan M., Fujimoto, Junya, Bishop, Justin A., Yan, Shirley, Cai, Ling, Behrens, Carmen, Berry, Lynne D., Wilhelm, Clare, Aisner, Dara, Sholl, Lynette, Johnson, Bruce E., Kwiatkowski, David J., Wistuba, Ignacio I., Bunn, Paul A., Minna, John, Xiao, Guanghua, Kris, Mark G., Xie, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843059/
https://www.ncbi.nlm.nih.gov/pubmed/36647832
http://dx.doi.org/10.1172/JCI160330

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