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Treatment of pancreatic cancer with irreversible electroporation and intratumoral CD40 antibody stimulates systemic immune responses that inhibit liver metastasis in an orthotopic model

BACKGROUND: Pancreatic cancer (PC) has a poor prognosis, and most patients present with either locally advanced or distant metastatic disease. Irreversible electroporation (IRE) is a non-thermal method of ablation used clinically in locally advanced PC, but most patients eventually develop distant r...

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Detalles Bibliográficos
Autores principales: Shankara Narayanan, Jayanth S, Hayashi, Tomoko, Erdem, Suna, McArdle, Sara, Tiriac, Herve, Ray, Partha, Pu, Minya, Mikulski, Zbigniew, Miller, Aaron, Messer, Karen, Carson, Dennis, Schoenberger, Stephen, White, Rebekah R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843215/
https://www.ncbi.nlm.nih.gov/pubmed/36634919
http://dx.doi.org/10.1136/jitc-2022-006133