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Length biases in single-cell RNA sequencing of pre-mRNA
Single-cell RNA sequencing data can be modeled using Markov chains to yield genome-wide insights into transcriptional physics. However, quantitative inference with such data requires careful assessment of noise sources. We find that long pre-mRNA transcripts are over-represented in sequencing data....
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843228/ https://www.ncbi.nlm.nih.gov/pubmed/36660179 http://dx.doi.org/10.1016/j.bpr.2022.100097 |