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Exploring the mechanisms underlying the therapeutic effect of the drug pair Rhubarb-Coptis in diabetic nephropathy using network pharmacology and molecular docking analysis

BACKGROUND: To use network pharmacology to explore the mechanism of the drug pair Rhubarb-Coptis in the treatment of diabetic nephropathy (DN). METHODS: The Traditional Chinese Medicine Systems Pharmacology (TCMSP) database was used to screen active ingredients of drug pair Rhubarb-Coptis. Targets w...

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Detalles Bibliográficos
Autores principales: Wu, Chunwei, Cao, Lei, Liu, Miao, Zhang, Wenlong, Chen, Hailong, Wang, Ruolin, Liu, Chang, He, Ze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843313/
https://www.ncbi.nlm.nih.gov/pubmed/36660658
http://dx.doi.org/10.21037/atm-22-5550