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Perturbation of placental protein glycosylation by endoplasmic reticulum stress promotes maladaptation of maternal hepatic glucose metabolism

Placental hormones orchestrate maternal metabolic adaptations to support pregnancy. We hypothesized that placental ER stress, which characterizes early-onset pre-eclampsia (ePE), compromises glycosylation, reducing hormone bioactivity and these maladaptations predispose the mother to metabolic disea...

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Detalles Bibliográficos
Autores principales:	Yung, Hong Wa, Zhao, Xiaohui, Glover, Luke, Burrin, Charlotte, Pang, Poh-Choo, Jones, Carolyn J.P., Gill, Carolyn, Duhig, Kate, Olovsson, Matts, Chappell, Lucy C., Haslam, Stuart M., Dell, Anne, Burton, Graham J., Charnock-Jones, D. Stephen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843443/ https://www.ncbi.nlm.nih.gov/pubmed/36660474 http://dx.doi.org/10.1016/j.isci.2022.105911

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