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HDAC6 regulates human erythroid differentiation through modulation of JAK2 signalling

Among histone deacetylases, HDAC6 is unusual in its cytoplasmic localization. Its inhibition leads to hyperacetylation of non‐histone proteins, inhibiting cell cycle, proliferation and apoptosis. Ricolinostat (ACY‐1215) is a selective inhibitor of the histone deacetylase HDAC6 with proven efficacy i...

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Detalles Bibliográficos
Autores principales: Vong, Pascal, Messaoudi, Kahia, Jankovsky, Nicolas, Gomilla, Cathy, Demont, Yohann, Caulier, Alexis, Jedraszak, Guillaume, Demagny, Julien, Djordjevic, Stefan, Boyer, Thomas, Marolleau, Jean Pierre, Rochette, Jacques, Ouled‐Haddou, Hakim, Garçon, Loïc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843532/
https://www.ncbi.nlm.nih.gov/pubmed/36578217
http://dx.doi.org/10.1111/jcmm.17559

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