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Venous Stent Placement for Malignant Vena Cava Syndrome in a Patient with Liposarcoma

Patient: Female, 36-year-old Final Diagnosis: Malignant vena cava syndrome Symptoms: Lower leg edema Medication:— Clinical Procedure: Inferior vena cava stenting Specialty: Palliative Medicine • Radiology OBJECTIVE: Rare disease BACKGROUND: Reports of venous stenting for inferior vena cava (IVC) syn...

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Autores principales: Shiohira, Shunya, Sugiura, Toshihiko, Ikeda, Hideki, Iwasawa, Shunichiro, Akimoto, Yuto, Kasai, Hajime, Shikano, Kohei, Hino, Aoi, Saiga, Atsushi, Koizumi, Jun, Sekine, Yasuo, Suzuki, Takuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843648/
https://www.ncbi.nlm.nih.gov/pubmed/36627831
http://dx.doi.org/10.12659/AJCR.938311
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author Shiohira, Shunya
Sugiura, Toshihiko
Ikeda, Hideki
Iwasawa, Shunichiro
Akimoto, Yuto
Kasai, Hajime
Shikano, Kohei
Hino, Aoi
Saiga, Atsushi
Koizumi, Jun
Sekine, Yasuo
Suzuki, Takuji
author_facet Shiohira, Shunya
Sugiura, Toshihiko
Ikeda, Hideki
Iwasawa, Shunichiro
Akimoto, Yuto
Kasai, Hajime
Shikano, Kohei
Hino, Aoi
Saiga, Atsushi
Koizumi, Jun
Sekine, Yasuo
Suzuki, Takuji
author_sort Shiohira, Shunya
collection PubMed
description Patient: Female, 36-year-old Final Diagnosis: Malignant vena cava syndrome Symptoms: Lower leg edema Medication:— Clinical Procedure: Inferior vena cava stenting Specialty: Palliative Medicine • Radiology OBJECTIVE: Rare disease BACKGROUND: Reports of venous stenting for inferior vena cava (IVC) syndrome (IVCS) due to sarcoma are limited, and the treatment’s efficacy and safety are not clear. CASE REPORT: A 36-year-old woman with myxoid liposarcoma was admitted to the Department of Respiratory Medicine for treatment of bilateral lower-leg edema and to be evaluated for acute liver dysfunction. She was 13 years old when she was diagnosed with myxoid liposarcoma. Over the next 18 years, she had 4 tumor resections and 1 round of radiation therapy. She had been on chemotherapy for 4 years and then pazopanib at the age of 35. The edema did not improve after admission despite treatment with diuretics. Computed tomography revealed a huge liposarcoma occupying the right thoracic cavity and a compressed IVC, which caused the edema. Although doxorubicin was administered as fifth-line treatment, there was no response. Since there was no additional chemotherapy regimen, her prognosis was considered to be less than 6 months. She could not be discharged to her home since she was unable to walk due to the edema; therefore, IVC stenting was performed to improve her dysmotility. After IVC stenting, the lower-leg edema improved without any adverse events, enabling her to walk and eventually return home. CONCLUSIONS: In patients with IVCS caused by rare malignancies such as myxoid liposarcoma, an IVC stent can be safely implanted and can help to alleviate symptoms. IVC stenting can improve symptoms and allow for home care, resulting in improved quality of life.
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spelling pubmed-98436482023-02-02 Venous Stent Placement for Malignant Vena Cava Syndrome in a Patient with Liposarcoma Shiohira, Shunya Sugiura, Toshihiko Ikeda, Hideki Iwasawa, Shunichiro Akimoto, Yuto Kasai, Hajime Shikano, Kohei Hino, Aoi Saiga, Atsushi Koizumi, Jun Sekine, Yasuo Suzuki, Takuji Am J Case Rep Articles Patient: Female, 36-year-old Final Diagnosis: Malignant vena cava syndrome Symptoms: Lower leg edema Medication:— Clinical Procedure: Inferior vena cava stenting Specialty: Palliative Medicine • Radiology OBJECTIVE: Rare disease BACKGROUND: Reports of venous stenting for inferior vena cava (IVC) syndrome (IVCS) due to sarcoma are limited, and the treatment’s efficacy and safety are not clear. CASE REPORT: A 36-year-old woman with myxoid liposarcoma was admitted to the Department of Respiratory Medicine for treatment of bilateral lower-leg edema and to be evaluated for acute liver dysfunction. She was 13 years old when she was diagnosed with myxoid liposarcoma. Over the next 18 years, she had 4 tumor resections and 1 round of radiation therapy. She had been on chemotherapy for 4 years and then pazopanib at the age of 35. The edema did not improve after admission despite treatment with diuretics. Computed tomography revealed a huge liposarcoma occupying the right thoracic cavity and a compressed IVC, which caused the edema. Although doxorubicin was administered as fifth-line treatment, there was no response. Since there was no additional chemotherapy regimen, her prognosis was considered to be less than 6 months. She could not be discharged to her home since she was unable to walk due to the edema; therefore, IVC stenting was performed to improve her dysmotility. After IVC stenting, the lower-leg edema improved without any adverse events, enabling her to walk and eventually return home. CONCLUSIONS: In patients with IVCS caused by rare malignancies such as myxoid liposarcoma, an IVC stent can be safely implanted and can help to alleviate symptoms. IVC stenting can improve symptoms and allow for home care, resulting in improved quality of life. International Scientific Literature, Inc. 2023-01-11 /pmc/articles/PMC9843648/ /pubmed/36627831 http://dx.doi.org/10.12659/AJCR.938311 Text en © Am J Case Rep, 2023 https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Articles
Shiohira, Shunya
Sugiura, Toshihiko
Ikeda, Hideki
Iwasawa, Shunichiro
Akimoto, Yuto
Kasai, Hajime
Shikano, Kohei
Hino, Aoi
Saiga, Atsushi
Koizumi, Jun
Sekine, Yasuo
Suzuki, Takuji
Venous Stent Placement for Malignant Vena Cava Syndrome in a Patient with Liposarcoma
title Venous Stent Placement for Malignant Vena Cava Syndrome in a Patient with Liposarcoma
title_full Venous Stent Placement for Malignant Vena Cava Syndrome in a Patient with Liposarcoma
title_fullStr Venous Stent Placement for Malignant Vena Cava Syndrome in a Patient with Liposarcoma
title_full_unstemmed Venous Stent Placement for Malignant Vena Cava Syndrome in a Patient with Liposarcoma
title_short Venous Stent Placement for Malignant Vena Cava Syndrome in a Patient with Liposarcoma
title_sort venous stent placement for malignant vena cava syndrome in a patient with liposarcoma
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843648/
https://www.ncbi.nlm.nih.gov/pubmed/36627831
http://dx.doi.org/10.12659/AJCR.938311
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