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Relation of ACE2 with co-morbidity factors in SARS-CoV-2 pathogenicity
In the last 3 years of the pandemic situation, SARS-CoV-2 caused a significant number of deaths. Infection rates for symptomatic and asymptomatic patients are higher than that for death. Eventually, researchers explored that the major deaths are attributed to several comorbidity factors. The confoun...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer London
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843654/ https://www.ncbi.nlm.nih.gov/pubmed/36687210 http://dx.doi.org/10.1007/s00580-023-03434-9 |
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author | Santra, Dipannita Banerjee, Amrita De, Subrata Kr. Thatoi, Hrudayanath Maiti, Smarajit |
author_facet | Santra, Dipannita Banerjee, Amrita De, Subrata Kr. Thatoi, Hrudayanath Maiti, Smarajit |
author_sort | Santra, Dipannita |
collection | PubMed |
description | In the last 3 years of the pandemic situation, SARS-CoV-2 caused a significant number of deaths. Infection rates for symptomatic and asymptomatic patients are higher than that for death. Eventually, researchers explored that the major deaths are attributed to several comorbidity factors. The confounding factors and gender-associated infection/death rate are observed globally. This suggests that SARS-CoV-2 selects the human system recognizing the internal comorbid environment. This article explored the influences of hypertension, diabetes, cardiovascular, and renovascular disorders in COVID-19 severity and mortality. Brief mechanistic layouts have been presented here, indicating some of the comorbidity as the critical determinant in the COVID-19 pathogenesis and related mortality. |
format | Online Article Text |
id | pubmed-9843654 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer London |
record_format | MEDLINE/PubMed |
spelling | pubmed-98436542023-01-17 Relation of ACE2 with co-morbidity factors in SARS-CoV-2 pathogenicity Santra, Dipannita Banerjee, Amrita De, Subrata Kr. Thatoi, Hrudayanath Maiti, Smarajit Comp Clin Path Review Article In the last 3 years of the pandemic situation, SARS-CoV-2 caused a significant number of deaths. Infection rates for symptomatic and asymptomatic patients are higher than that for death. Eventually, researchers explored that the major deaths are attributed to several comorbidity factors. The confounding factors and gender-associated infection/death rate are observed globally. This suggests that SARS-CoV-2 selects the human system recognizing the internal comorbid environment. This article explored the influences of hypertension, diabetes, cardiovascular, and renovascular disorders in COVID-19 severity and mortality. Brief mechanistic layouts have been presented here, indicating some of the comorbidity as the critical determinant in the COVID-19 pathogenesis and related mortality. Springer London 2023-01-17 2023 /pmc/articles/PMC9843654/ /pubmed/36687210 http://dx.doi.org/10.1007/s00580-023-03434-9 Text en © The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Review Article Santra, Dipannita Banerjee, Amrita De, Subrata Kr. Thatoi, Hrudayanath Maiti, Smarajit Relation of ACE2 with co-morbidity factors in SARS-CoV-2 pathogenicity |
title | Relation of ACE2 with co-morbidity factors in SARS-CoV-2 pathogenicity |
title_full | Relation of ACE2 with co-morbidity factors in SARS-CoV-2 pathogenicity |
title_fullStr | Relation of ACE2 with co-morbidity factors in SARS-CoV-2 pathogenicity |
title_full_unstemmed | Relation of ACE2 with co-morbidity factors in SARS-CoV-2 pathogenicity |
title_short | Relation of ACE2 with co-morbidity factors in SARS-CoV-2 pathogenicity |
title_sort | relation of ace2 with co-morbidity factors in sars-cov-2 pathogenicity |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843654/ https://www.ncbi.nlm.nih.gov/pubmed/36687210 http://dx.doi.org/10.1007/s00580-023-03434-9 |
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