Engineered exosomes enriched in netrin-1 modRNA promote axonal growth in spinal cord injury by attenuating inflammation and pyroptosis

BACKGROUND: Spinal cord injury (SCI) brings a heavy burden to individuals and society, and there is no effective treatment at present. Exosomes (EX) are cell secreted vesicles containing molecules such as nucleic acids and proteins, which hold promise for the treatment of SCI. Netrin-1 is an axon gu...

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Detalles Bibliográficos
Autores principales: Lu, Xiao, Xu, Guangyu, Lin, Zhidi, Zou, Fei, Liu, Siyang, Zhang, Yuxuan, Fu, Wei, Jiang, Jianyuan, Ma, Xiaosheng, Song, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843879/
https://www.ncbi.nlm.nih.gov/pubmed/36647161
http://dx.doi.org/10.1186/s40824-023-00339-0

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