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PDA-PRGCN: identification of Piwi-interacting RNA-disease associations through subgraph projection and residual scaling-based feature augmentation

BACKGROUND: Emerging evidences show that Piwi-interacting RNAs (piRNAs) play a pivotal role in numerous complex human diseases. Identifying potential piRNA-disease associations (PDAs) is crucial for understanding disease pathogenesis at molecular level. Compared to the biological wet experiments, th...

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Detalles Bibliográficos
Autores principales: Zhang, Ping, Sun, Weicheng, Wei, Dengguo, Li, Guodong, Xu, Jinsheng, You, Zhuhong, Zhao, Bowei, Li, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843905/
https://www.ncbi.nlm.nih.gov/pubmed/36650439
http://dx.doi.org/10.1186/s12859-022-05073-3

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