Occurrence of variants of unknown clinical significance in genetic testing for hereditary breast and ovarian cancer syndrome and Lynch syndrome: a literature review and analytical observational retrospective cohort study

BACKGROUND AND PURPOSE: Over the last decade, the implementation of multigene panels for hereditary tumor syndrome has increased at our institution (Inselspital, University Hospital Berne, Switzerland). The aim of this study was to determine the prevalence of variants of unknown significance (VUS) i...

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Detalles Bibliográficos
Autores principales: Adam, Felicia, Fluri, Muriel, Scherz, Amina, Rabaglio, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843935/
https://www.ncbi.nlm.nih.gov/pubmed/36647026
http://dx.doi.org/10.1186/s12920-023-01437-7

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