Langerhans Cell Histiocytosis of the Orbit Presenting as Periorbital Cellulitis

Langerhans cell histiocytosis (LCH) is a rare disease of the reticuloendothelial system. It is characterized by misguided differentiation of myeloid dendritic cell precursors. LCH most commonly presents in childhood and the clinical presentation is dependent on the site and extent of organ involveme...

Descripción completa

Detalles Bibliográficos
Autores principales: Anwar, Mohammad, Eltayef, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Ophthalmology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844022/
https://www.ncbi.nlm.nih.gov/pubmed/36654630
http://dx.doi.org/10.7759/cureus.32656
_version_ 1784870529757347840
author Anwar, Mohammad
Eltayef, Mohamed
author_facet Anwar, Mohammad
Eltayef, Mohamed
author_sort Anwar, Mohammad
collection PubMed
description Langerhans cell histiocytosis (LCH) is a rare disease of the reticuloendothelial system. It is characterized by misguided differentiation of myeloid dendritic cell precursors. LCH most commonly presents in childhood and the clinical presentation is dependent on the site and extent of organ involvement. We report a case of orbital Langerhans cell histiocytosis in a 12-year-old boy who presented with left periorbital cellulitis with subsequent proptosis. He later underwent a successful left orbital-frontal-temporal craniotomy and is currently undergoing postoperative chemotherapy.
format Online
Article
Text
id pubmed-9844022
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-98440222023-01-17 Langerhans Cell Histiocytosis of the Orbit Presenting as Periorbital Cellulitis Anwar, Mohammad Eltayef, Mohamed Cureus Ophthalmology Langerhans cell histiocytosis (LCH) is a rare disease of the reticuloendothelial system. It is characterized by misguided differentiation of myeloid dendritic cell precursors. LCH most commonly presents in childhood and the clinical presentation is dependent on the site and extent of organ involvement. We report a case of orbital Langerhans cell histiocytosis in a 12-year-old boy who presented with left periorbital cellulitis with subsequent proptosis. He later underwent a successful left orbital-frontal-temporal craniotomy and is currently undergoing postoperative chemotherapy. Cureus 2022-12-18 /pmc/articles/PMC9844022/ /pubmed/36654630 http://dx.doi.org/10.7759/cureus.32656 Text en Copyright © 2022, Anwar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Ophthalmology
Anwar, Mohammad
Eltayef, Mohamed
Langerhans Cell Histiocytosis of the Orbit Presenting as Periorbital Cellulitis
title Langerhans Cell Histiocytosis of the Orbit Presenting as Periorbital Cellulitis
title_full Langerhans Cell Histiocytosis of the Orbit Presenting as Periorbital Cellulitis
title_fullStr Langerhans Cell Histiocytosis of the Orbit Presenting as Periorbital Cellulitis
title_full_unstemmed Langerhans Cell Histiocytosis of the Orbit Presenting as Periorbital Cellulitis
title_short Langerhans Cell Histiocytosis of the Orbit Presenting as Periorbital Cellulitis
title_sort langerhans cell histiocytosis of the orbit presenting as periorbital cellulitis
topic Ophthalmology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844022/
https://www.ncbi.nlm.nih.gov/pubmed/36654630
http://dx.doi.org/10.7759/cureus.32656
work_keys_str_mv AT anwarmohammad langerhanscellhistiocytosisoftheorbitpresentingasperiorbitalcellulitis
AT eltayefmohamed langerhanscellhistiocytosisoftheorbitpresentingasperiorbitalcellulitis

Ejemplares similares