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Rapid transmission and tight bottlenecks constrain the evolution of highly transmissible SARS-CoV-2 variants
Transmission bottlenecks limit the spread of novel mutations and reduce the efficiency of selection along a transmission chain. While increased force of infection, receptor binding, or immune evasion may influence bottleneck size, the relationship between transmissibility and the transmission bottle...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844183/ https://www.ncbi.nlm.nih.gov/pubmed/36650162 http://dx.doi.org/10.1038/s41467-023-36001-5 |