Rapid transmission and tight bottlenecks constrain the evolution of highly transmissible SARS-CoV-2 variants

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Transmission bottlenecks limit the spread of novel mutations and reduce the efficiency of selection along a transmission chain. While increased force of infection, receptor binding, or immune evasion may influence bottleneck size, the relationship between transmissibility and the transmission bottle...

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Detalles Bibliográficos
Autores principales: Bendall, Emily E., Callear, Amy P., Getz, Amy, Goforth, Kendra, Edwards, Drew, Monto, Arnold S., Martin, Emily T., Lauring, Adam S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844183/
https://www.ncbi.nlm.nih.gov/pubmed/36650162
http://dx.doi.org/10.1038/s41467-023-36001-5
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