Highly Accessible Computational Prediction and In Vivo/In Vitro Experimental Validation: Novel Synthetic Phenyl Ketone Derivatives as Promising Agents against NAFLD via Modulating Oxidoreductase Activity

Nonalcoholic fatty liver disease (NAFLD) has reached epidemic proportions with no pharmacological treatment approved. Several highly accessible computational tools were employed to predict the activities of twelve novel compounds prior to actual chemical synthesis. We began our work by designing two...

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Detalles Bibliográficos
Autores principales: Qiao, Yanan, Deng, Huifang, Liu, Lihua, Liu, Shuran, Ren, Luyao, Shi, Chuandao, Chen, Xi, Guan, Lixia, Liu, Weiran, Li, Zehua, Li, Yunlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844233/
https://www.ncbi.nlm.nih.gov/pubmed/36659905
http://dx.doi.org/10.1155/2023/3782230

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