High Throughput FISH Screening Identifies Small Molecules That Modulate Oncogenic lncRNA MALAT1 via GSK3B and hnRNPs

Traditionally, small molecule-based drug discovery has mainly focused on proteins as the drug target. Opening RNA as an additional target space for small molecules offers the possibility to therapeutically modulate disease-driving non-coding RNA targets as well as mRNA of otherwise undruggable prote...

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Detalles Bibliográficos
Autores principales: Zablowsky, Nina, Farack, Lydia, Rofall, Sven, Kramer, Jan, Meyer, Hanna, Nguyen, Duy, Ulrich, Alexander K. C., Bader, Benjamin, Steigemann, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844399/
https://www.ncbi.nlm.nih.gov/pubmed/36649031
http://dx.doi.org/10.3390/ncrna9010002

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