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Identifying Gut Microbiota Conditions Associated with Disease in the African Continent: A Scoping Review Protocol
The gut microbiota has been immensely studied over the past years because of its involvement in the pathogenesis of numerous diseases. However, gut microbiota data in Africa are limited. Therefore, it is crucial to have studies that reflect various populations in order to fully capture global microb...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844410/ https://www.ncbi.nlm.nih.gov/pubmed/36648951 http://dx.doi.org/10.3390/mps6010002 |
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author | Pheeha, Sara M. Tamuzi, Jacques L. Manda, Samuel Nyasulu, Peter S. |
author_facet | Pheeha, Sara M. Tamuzi, Jacques L. Manda, Samuel Nyasulu, Peter S. |
author_sort | Pheeha, Sara M. |
collection | PubMed |
description | The gut microbiota has been immensely studied over the past years because of its involvement in the pathogenesis of numerous diseases. However, gut microbiota data in Africa are limited. Therefore, it is crucial to have studies that reflect various populations in order to fully capture global microbial diversity. In the proposed scoping review, we will describe the gut microbiota’s appearance in terms of gut microbiota markers, in both health and disease in African populations. Relevant publications will be searched for in the PubMed, Scopus, Web of Science, Academic Search Premier, Africa-Wide Information, African journals online, CINAHL, and EBSCOhost and Embase databases. We will focus on articles published between January 2005 and March 2023. We will also determine if the studies to be included in the review would provide enough data to identify quantifiable gut microbiome traits that could be used as health or disease markers, identify the types of diseases that were mostly focused on in relation to gut microbiota research in Africa, as well as to discover and analyze knowledge gaps in the gut microbiota research field in the continent. We will include studies involving African countries regardless of race, gender, age, health status, disease type, study design, or care setting. Two reviewers will conduct a literature search and screen the titles/abstracts against the eligibility criteria. The reviewers will subsequently screen full-text articles and identify studies that meet the inclusion criteria. This will be followed by charting the data using a charting tool and analysis of the evidence. The proposed scoping review will follow a qualitative approach such that a narrative summary will accompany the tabulated/graphical results which will describe how the results relate to the review objectives and questions. As a result, this review may play a significant role in the identification of microbiota-related adjunctive therapies in the African region where multiple comorbidities coexist. Scoping review registration: Open Science Framework. |
format | Online Article Text |
id | pubmed-9844410 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98444102023-01-18 Identifying Gut Microbiota Conditions Associated with Disease in the African Continent: A Scoping Review Protocol Pheeha, Sara M. Tamuzi, Jacques L. Manda, Samuel Nyasulu, Peter S. Methods Protoc Protocol The gut microbiota has been immensely studied over the past years because of its involvement in the pathogenesis of numerous diseases. However, gut microbiota data in Africa are limited. Therefore, it is crucial to have studies that reflect various populations in order to fully capture global microbial diversity. In the proposed scoping review, we will describe the gut microbiota’s appearance in terms of gut microbiota markers, in both health and disease in African populations. Relevant publications will be searched for in the PubMed, Scopus, Web of Science, Academic Search Premier, Africa-Wide Information, African journals online, CINAHL, and EBSCOhost and Embase databases. We will focus on articles published between January 2005 and March 2023. We will also determine if the studies to be included in the review would provide enough data to identify quantifiable gut microbiome traits that could be used as health or disease markers, identify the types of diseases that were mostly focused on in relation to gut microbiota research in Africa, as well as to discover and analyze knowledge gaps in the gut microbiota research field in the continent. We will include studies involving African countries regardless of race, gender, age, health status, disease type, study design, or care setting. Two reviewers will conduct a literature search and screen the titles/abstracts against the eligibility criteria. The reviewers will subsequently screen full-text articles and identify studies that meet the inclusion criteria. This will be followed by charting the data using a charting tool and analysis of the evidence. The proposed scoping review will follow a qualitative approach such that a narrative summary will accompany the tabulated/graphical results which will describe how the results relate to the review objectives and questions. As a result, this review may play a significant role in the identification of microbiota-related adjunctive therapies in the African region where multiple comorbidities coexist. Scoping review registration: Open Science Framework. MDPI 2022-12-24 /pmc/articles/PMC9844410/ /pubmed/36648951 http://dx.doi.org/10.3390/mps6010002 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Protocol Pheeha, Sara M. Tamuzi, Jacques L. Manda, Samuel Nyasulu, Peter S. Identifying Gut Microbiota Conditions Associated with Disease in the African Continent: A Scoping Review Protocol |
title | Identifying Gut Microbiota Conditions Associated with Disease in the African Continent: A Scoping Review Protocol |
title_full | Identifying Gut Microbiota Conditions Associated with Disease in the African Continent: A Scoping Review Protocol |
title_fullStr | Identifying Gut Microbiota Conditions Associated with Disease in the African Continent: A Scoping Review Protocol |
title_full_unstemmed | Identifying Gut Microbiota Conditions Associated with Disease in the African Continent: A Scoping Review Protocol |
title_short | Identifying Gut Microbiota Conditions Associated with Disease in the African Continent: A Scoping Review Protocol |
title_sort | identifying gut microbiota conditions associated with disease in the african continent: a scoping review protocol |
topic | Protocol |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844410/ https://www.ncbi.nlm.nih.gov/pubmed/36648951 http://dx.doi.org/10.3390/mps6010002 |
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