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Impact of COVID-19 on Patients Hospitalized with ST-Segment Elevation Myocardial Infarction in the United States during the Early Pandemic: An Analysis of Outcomes, Care Delivery, and Racial Disparities in Mortality

The COVID-19 pandemic has impacted healthcare delivery to patients with ST-segment elevation myocardial infarction (STEMI). The aim of our retrospective study was to determine the effect of COVID-19 on inpatient STEMI outcomes and to investigate changes in cardiac care delivery during 2020. We utili...

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Autores principales: Majeed, Harris, Gangu, Karthik, Shekhar, Rahul, Sagheer, Shazib, Garg, Ishan, Shuja, Hina, Bobba, Aniesh, Chourasia, Prabal, Avula, Sindhu Reddy, Sheikh, Abu Baker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844427/
https://www.ncbi.nlm.nih.gov/pubmed/36648860
http://dx.doi.org/10.3390/idr15010006
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author Majeed, Harris
Gangu, Karthik
Shekhar, Rahul
Sagheer, Shazib
Garg, Ishan
Shuja, Hina
Bobba, Aniesh
Chourasia, Prabal
Avula, Sindhu Reddy
Sheikh, Abu Baker
author_facet Majeed, Harris
Gangu, Karthik
Shekhar, Rahul
Sagheer, Shazib
Garg, Ishan
Shuja, Hina
Bobba, Aniesh
Chourasia, Prabal
Avula, Sindhu Reddy
Sheikh, Abu Baker
author_sort Majeed, Harris
collection PubMed
description The COVID-19 pandemic has impacted healthcare delivery to patients with ST-segment elevation myocardial infarction (STEMI). The aim of our retrospective study was to determine the effect of COVID-19 on inpatient STEMI outcomes and to investigate changes in cardiac care delivery during 2020. We utilized the National Inpatient Sample database to examine inpatient mortality and cardiac procedures among STEMI patients with and without COVID-19. In our study, STEMI patients with COVID-19 had higher inpatient mortality (47.4% vs. 11.2%, aOR: 3.8, 95% CI: 3.2–4.6, p < 0.001), increased length of stay (9.0 days vs. 4.3 days, p < 0.001) and higher cost of hospitalization (USD 172,518 vs. USD 131,841, p = 0.004) when compared to STEMI patients without COVID-19. STEMI patients with COVID-19 also received significantly less invasive cardiac procedures (coronary angiograms: 30.4% vs. 50.8%, p < 0.001; PCI: 32.9% vs. 70.1%, p < 0.001; CABG: 0.9% vs. 4.1%, p < 0.001) and were more likely to receive systemic thrombolytic therapy (4.2% vs. 1.1%, p < 0.001) when compared to STEMI patients without COVID-19. Our findings are the result of complications of SARS-CoV2 infection as well as alterations in healthcare delivery due to the burden of the COVID-19 pandemic.
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spelling pubmed-98444272023-01-18 Impact of COVID-19 on Patients Hospitalized with ST-Segment Elevation Myocardial Infarction in the United States during the Early Pandemic: An Analysis of Outcomes, Care Delivery, and Racial Disparities in Mortality Majeed, Harris Gangu, Karthik Shekhar, Rahul Sagheer, Shazib Garg, Ishan Shuja, Hina Bobba, Aniesh Chourasia, Prabal Avula, Sindhu Reddy Sheikh, Abu Baker Infect Dis Rep Review The COVID-19 pandemic has impacted healthcare delivery to patients with ST-segment elevation myocardial infarction (STEMI). The aim of our retrospective study was to determine the effect of COVID-19 on inpatient STEMI outcomes and to investigate changes in cardiac care delivery during 2020. We utilized the National Inpatient Sample database to examine inpatient mortality and cardiac procedures among STEMI patients with and without COVID-19. In our study, STEMI patients with COVID-19 had higher inpatient mortality (47.4% vs. 11.2%, aOR: 3.8, 95% CI: 3.2–4.6, p < 0.001), increased length of stay (9.0 days vs. 4.3 days, p < 0.001) and higher cost of hospitalization (USD 172,518 vs. USD 131,841, p = 0.004) when compared to STEMI patients without COVID-19. STEMI patients with COVID-19 also received significantly less invasive cardiac procedures (coronary angiograms: 30.4% vs. 50.8%, p < 0.001; PCI: 32.9% vs. 70.1%, p < 0.001; CABG: 0.9% vs. 4.1%, p < 0.001) and were more likely to receive systemic thrombolytic therapy (4.2% vs. 1.1%, p < 0.001) when compared to STEMI patients without COVID-19. Our findings are the result of complications of SARS-CoV2 infection as well as alterations in healthcare delivery due to the burden of the COVID-19 pandemic. MDPI 2023-01-06 /pmc/articles/PMC9844427/ /pubmed/36648860 http://dx.doi.org/10.3390/idr15010006 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Majeed, Harris
Gangu, Karthik
Shekhar, Rahul
Sagheer, Shazib
Garg, Ishan
Shuja, Hina
Bobba, Aniesh
Chourasia, Prabal
Avula, Sindhu Reddy
Sheikh, Abu Baker
Impact of COVID-19 on Patients Hospitalized with ST-Segment Elevation Myocardial Infarction in the United States during the Early Pandemic: An Analysis of Outcomes, Care Delivery, and Racial Disparities in Mortality
title Impact of COVID-19 on Patients Hospitalized with ST-Segment Elevation Myocardial Infarction in the United States during the Early Pandemic: An Analysis of Outcomes, Care Delivery, and Racial Disparities in Mortality
title_full Impact of COVID-19 on Patients Hospitalized with ST-Segment Elevation Myocardial Infarction in the United States during the Early Pandemic: An Analysis of Outcomes, Care Delivery, and Racial Disparities in Mortality
title_fullStr Impact of COVID-19 on Patients Hospitalized with ST-Segment Elevation Myocardial Infarction in the United States during the Early Pandemic: An Analysis of Outcomes, Care Delivery, and Racial Disparities in Mortality
title_full_unstemmed Impact of COVID-19 on Patients Hospitalized with ST-Segment Elevation Myocardial Infarction in the United States during the Early Pandemic: An Analysis of Outcomes, Care Delivery, and Racial Disparities in Mortality
title_short Impact of COVID-19 on Patients Hospitalized with ST-Segment Elevation Myocardial Infarction in the United States during the Early Pandemic: An Analysis of Outcomes, Care Delivery, and Racial Disparities in Mortality
title_sort impact of covid-19 on patients hospitalized with st-segment elevation myocardial infarction in the united states during the early pandemic: an analysis of outcomes, care delivery, and racial disparities in mortality
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844427/
https://www.ncbi.nlm.nih.gov/pubmed/36648860
http://dx.doi.org/10.3390/idr15010006
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