Cargando…

Serum metabolomics strategy for investigating the hepatotoxicity induced by different exposure times and doses of Gynura segetum (Lour.) Merr. in rats based on GC-MS

Gynura segetum (Lour.) Merr. (GS), has been widely used in Chinese folk medicine and can promote circulation, relieve pain and remove stasis. In recent years, the hepatotoxicity caused by GS has been reported, however its mechanism is not fully elucidated. Metabolomic techniques are powerful means t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Ying, Tian, Yingxin, Wang, Qixue, Gu, Xinyi, Chen, Long, Jia, Yiqun, Cao, Shan, Zhang, Ting, Zhou, Mingmei, Gou, Xiaojun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844675/ https://www.ncbi.nlm.nih.gov/pubmed/36741154 http://dx.doi.org/10.1039/d2ra07269f

Ejemplares similares

Investigation of Gynura segetum root extract (GSrE) induced hepatotoxicity based on metabolomic signatures and microbial community profiling in rats
por: Gu, Xinyi, et al.
Publicado: (2022)

The Anti-Cancer Property of Proteins Extracted from Gynura procumbens (Lour.) Merr
por: Hew, Chaw-Sen, et al.
Publicado: (2013)

Production of biomass and flavonoid of Gynura procumbens (Lour.) Merr shoots culture in temporary immersion system
por: Pramita, Ayu Dewi, et al.
Publicado: (2018)

UHPLC-ESI-Orbitrap-MS Analysis of Biologically Active Extracts from Gynura procumbens (Lour.) Merr. and Cleome gynandra L. Leaves
por: Chandradevan, Machap, et al.
Publicado: (2020)

Effects of bicyclol on hepatic sinusoidal obstruction syndrome induced by Gynura segetum
por: Yao, Jianzuo, et al.
Publicado: (2022)

Effects of Different Colored LEDs on the Enhancement of Biologically Active Ingredients in Callus Cultures of Gynura procumbens (Lour.) Merr.
por: Lian, Thang Tung, et al.
Publicado: (2019)

Phytochemical and Biological Investigation of an Indigenous Plant of Bangladesh, Gynura procumbens (Lour.) Merr.: Drug Discovery from Nature
por: Jobaer, Md. Abu, et al.
Publicado: (2023)

Hepatic veno-occlusive disease related to Gynura segetum: A case report
por: Sun, Ziyi, et al.
Publicado: (2018)

Gynura segetum induces hepatic sinusoidal obstruction syndrome in mice by impairing autophagy
por: Zhang, Hui, et al.
Publicado: (2022)

Screening of endophytic bacteria isolated from leaves of Sambung Nyawa [Gynura procumbens (Lour.) Merr.] for cytokinin-like compounds
por: Bhore, Subhash J, et al.
Publicado: (2010)

Effect of Cadmium and Copper Exposure on Growth, Secondary Metabolites and Antioxidant Activity in the Medicinal Plant Sambung Nyawa (Gynura procumbens (Lour.) Merr)
por: Ibrahim, Mohd Hafiz, et al.
Publicado: (2017)

Risk factors for hepatic veno-occlusive disease caused by Gynura segetum: a retrospective study
por: Wang, Yan, et al.
Publicado: (2018)

Transjugular intrahepatic portosystemic shunt for hepatic sinusoidal obstruction syndrome associated with consumption of Gynura segetum
por: Zhang, Lijie, et al.
Publicado: (2021)

Gynura segetum-induced liver injury leading to acute liver failure: a case report and literature review
por: Zhang, Zilong, et al.
Publicado: (2022)

Hepatic sinusoidal obstruction syndrome caused by the ingestion of Gynura segetum in a patient with alcoholic cirrhosis: a case report
por: Cen, Panpan, et al.
Publicado: (2021)

Correction: Thang et al. Effects of Different Colored LEDs on the Enhancement of Biologically Active Ingredients in Callus Cultures of Gynura procumbens (Lour.) Merr. Molecules 2019, 24, 4336
por: Lian, Thang Tung, et al.
Publicado: (2023)

A urinary metabolomics (GC-MS) strategy to evaluate the antidepressant-like effect of chlorogenic acid in adrenocorticotropic hormone-treated rats
por: Zhao, Le, et al.
Publicado: (2018)

Phosphocreatine attenuates Gynura segetum-induced hepatocyte apoptosis via a SIRT3-SOD2-mitochondrial reactive oxygen species pathway
por: Li, Dong-Ping, et al.
Publicado: (2019)

Characterization of the complete chloroplast genome of Carallia brachiata (Lour.) Merr. (Rhizophoraceae)
por: Zhou, You, et al.
Publicado: (2023)

Investigation of the idiosyncratic hepatotoxicity of Polygonum multiflorum Thunb. through metabolomics using GC-MS
por: Lin, Yan, et al.
Publicado: (2021)

Gynura procumbens Merr. decreases blood pressure in rats by vasodilatation via inhibition of calcium channels
por: Hoe, See‐Ziau, et al.
Publicado: (2011)

Comparative phytochemical profiling of different soybean (Glycine max (L.) Merr) genotypes using GC–MS
por: Alghamdi, Salem S., et al.
Publicado: (2018)

Comparison of Volatile Oil between the Fruits of Amomum villosum Lour. and Amomum villosum Lour. var. xanthioides T. L. Wu et Senjen Based on GC-MS and Chemometric Techniques
por: Ao, Hui, et al.
Publicado: (2019)

An in vivo and in silico evaluation of the hepatoprotective potential of Gynura procumbens: A promising agent for combating hepatotoxicity
por: Tithi, Tanzia Islam, et al.
Publicado: (2023)

Temperature Dependent Growth and Mortality of Agrotis segetum
por: Esbjerg, Peter, et al.
Publicado: (2019)

GC-MS Study of the Chemical Components of Different Aquilaria sinensis (Lour.) Gilgorgans and Agarwood from Different Asian Countries
por: Wang, Meng-Ru, et al.
Publicado: (2018)

Lasianosides A–E: New Iridoid Glucosides from the Leaves of Lasianthus verticillatus (Lour.) Merr. and Their Antioxidant Activity
por: Al-Hamoud, Gadah Abdulaziz, et al.
Publicado: (2019)

Metabolomics Benefits from Orbitrap GC–MS—Comparison of Low- and High-Resolution GC–MS
por: Stettin, Daniel, et al.
Publicado: (2020)

Rice Cakes Containing Dietary Fiber Supplemented with or without Artemisia Annua and Gynura Procumbens Merr. Alleviated the Risk Factors of Metabolic Syndrome
por: Yoon, Na Rae, et al.
Publicado: (2016)

Aqueous root extract of Asparagus cochinchinensis (Lour.) Merr. Has antioxidant activity in D-galactose-induced aging mice
por: Lei, Linghua, et al.
Publicado: (2017)

Organization of GC/MS and LC/MS metabolomics data into chemical libraries
por: DeHaven, Corey D, et al.
Publicado: (2010)

LC-MS and GC-MS based metabolomics platform for cancer research
por: Lu, Wenyun, et al.
Publicado: (2014)

Defining Blood Plasma and Serum Metabolome by GC-MS
por: Kiseleva, Olga, et al.
Publicado: (2021)

Geoherbalism Metabolomic Analysis of Atractylodes lancea (Thunb.) DC. by LC-Triple TOF-MS/MS and GC-MS
por: Qiu, Hailong, et al.
Publicado: (2023)

Preformulation Study of Pugun Tano (Curanga fel-terrae [Lour.] Merr) Ethanolic Extract Granule Mass in Capsule as Hepatoprotective Drug
por: Harahap, Urip, et al.
Publicado: (2019)

Identify potential allelochemicals from Humulus scandens (Lour.) Merr. root extracts that induce allelopathy on Alternanthera philoxeroides (Mart.) Griseb.
por: Wang, Lichao, et al.
Publicado: (2021)

The complete chloroplast genome of two traditional medical plants: Asparagus cochinchinensis (Lour.) Merr. and Asparagus dauricus Fisch. ex Link
por: Sheng, Wentao
Publicado: (2022)

Antioxidant Potential in Different Parts and Callus of Gynura procumbens and Different Parts of Gynura bicolor
por: Krishnan, Vijendren, et al.
Publicado: (2015)

Metabolomic and elemental analysis of camel and bovine urine by GC–MS and ICP–MS
por: Ahamad, Syed Rizwan, et al.
Publicado: (2017)

Antiherpetic Effects of Gynura procumbens
por: Jarikasem, Siripen, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_m4bqi1j66kapvr811austh792s