Sustaining the T-cell activity in xenografted psoriasis skin

Xenografting of psoriasis skin onto immune deficient mice has been widely used to obtain proof-of-principle of new drug candidates. However, the lack of human T-cell activity in the grafts limits the use of the model. Here, we show that xenografting of lesional skin from psoriasis patients onto huma...

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Detalles Bibliográficos
Autores principales: Christensen, Pernille Kristine Fisker, Hansen, Axel Kornerup, Skov, Søren, Engkilde, Kåre, Larsen, Jesper, Høyer-Hansen, Maria Helena, Koch, Janne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844869/
https://www.ncbi.nlm.nih.gov/pubmed/36649237
http://dx.doi.org/10.1371/journal.pone.0278390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844869/
https://www.ncbi.nlm.nih.gov/pubmed/36649237
http://dx.doi.org/10.1371/journal.pone.0278390

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