Cargando…
Sustaining the T-cell activity in xenografted psoriasis skin
Xenografting of psoriasis skin onto immune deficient mice has been widely used to obtain proof-of-principle of new drug candidates. However, the lack of human T-cell activity in the grafts limits the use of the model. Here, we show that xenografting of lesional skin from psoriasis patients onto huma...
Autores principales: | Christensen, Pernille Kristine Fisker, Hansen, Axel Kornerup, Skov, Søren, Engkilde, Kåre, Larsen, Jesper, Høyer-Hansen, Maria Helena, Koch, Janne |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844869/ https://www.ncbi.nlm.nih.gov/pubmed/36649237 http://dx.doi.org/10.1371/journal.pone.0278390 |
Ejemplares similares
-
Imiquimod induces skin inflammation in humanized BRGSF mice with limited human immune cell activity
por: Christensen, Pernille Kristine Fisker, et al.
Publicado: (2023) -
Sensitivity to oxazolone induced dermatitis is transferable with gut microbiota in mice
por: Zachariassen, Line Fisker, et al.
Publicado: (2017) -
Effect of gluten-free diet and antibiotics on murine gut microbiota and immune response to tetanus vaccination
por: Kihl, Pernille, et al.
Publicado: (2022) -
Prevention of Diabetes in NOD Mice by Repeated Exposures to a Contact Allergen Inducing a Sub-Clinical Dermatitis
por: Engkilde, Kaare, et al.
Publicado: (2010) -
Initial joint bleed volume in a delayed on‐demand treatment setup correlates with subsequent synovial changes in hemophilic mice
por: Vøls, Kåre Kryger, et al.
Publicado: (2020)