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High tissue expression of TLRs combined with high density of tumor infiltrating lymphocytes predicts a better prognosis in colorectal cancer patients

BACKGROUND: Colorectal cancer causes 935,000 cancer deaths yearly. High local immune cell infiltration serves as a positive prognostic factor in CRC. Toll-like receptors (TLRs) induce innate immune responses and lead to adaptive immune system activation. TLRs play protumorigenic and antitumorigenic...

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Detalles Bibliográficos
Autores principales:	Beilmann-Lehtonen, Ines, Kasurinen, Jussi, Hagström, Jaana, Kaprio, Tuomas, Böckelman, Camilla, Haglund, Caj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844887/ https://www.ncbi.nlm.nih.gov/pubmed/36649244 http://dx.doi.org/10.1371/journal.pone.0280085

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