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Ureteral calculi in octogenarians and nonagenarians: Contemporary in-hospital management—A joint study by the endourological section of the Austrian Association of Urology
AIM: To assess contemporary in-hospital management of octogenarians and nonagenarians with ureteral calculi. MATERIALS AND METHODS: Review of patients aged ≥80 years hospitalized due to ureteral calculi. Data was extracted from eight Austrian centers of urology. Stone and patient related data were r...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844889/ https://www.ncbi.nlm.nih.gov/pubmed/36649250 http://dx.doi.org/10.1371/journal.pone.0280140 |
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author | Drerup, Martin Özsoy, Mehmet Wehrberger, Clemens Lenz, Matthias Ramesmayer, Christian Stolzlechner, Philipp Zanier, Johannes Falkensammer, C. E. Handjev, Ivan Wasserscheid, Andreas Seklehner, Stephan |
author_facet | Drerup, Martin Özsoy, Mehmet Wehrberger, Clemens Lenz, Matthias Ramesmayer, Christian Stolzlechner, Philipp Zanier, Johannes Falkensammer, C. E. Handjev, Ivan Wasserscheid, Andreas Seklehner, Stephan |
author_sort | Drerup, Martin |
collection | PubMed |
description | AIM: To assess contemporary in-hospital management of octogenarians and nonagenarians with ureteral calculi. MATERIALS AND METHODS: Review of patients aged ≥80 years hospitalized due to ureteral calculi. Data was extracted from eight Austrian centers of urology. Stone and patient related data were recorded. Treatment patterns in acute and elective settings were assessed. RESULTS: A total of 759 patients hospitalized with ureteral calculi were analyzed. Out of them, 643 were octogenarians (80-89years) and 116 nonagenarians (90–99 years). In an acute setting, simple de-obstruction with urinary diversions outnumbered active stone treatments like URS and SWL (62.6% vs. 26.9% vs. 10.5%). Decision making whether patients underwent active stone treatment was driven by stone location (OR = 0.28, p<0.0001), impaired renal function (OR = 0.28, p = 0.01) and indwelling urethral catheters (OR = 0.23, p = 0.01) but not by age or extend of mobility (all p>0.05). In elective settings, 81.5% of procedures were active stone treatments–mainly URS (76.9%), while DJ stent or nephrostomy replacements were noted in 14.2% and 4.3%. Octogenarians (OR = 14, p<0.0001) and patients capable of walking (OR = 4.51, p = 0.01) had significantly higher odds of receiving active stone. Stone free rates and complications rates with URS were similar between octogenarians and nonagenarians (p = 0.98 and p = 0.58). CONCLUSION: In acute settings, age and extend of mobility were not found to be independent predictors for active stone treatment. In elective settings, after having received urinary diversions, reduced mobility and nonagenarians were less likely to undergo stone removal treatments. Safety and efficacy of URS seems to be similar in octogenarians and nonagenarians. |
format | Online Article Text |
id | pubmed-9844889 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-98448892023-01-18 Ureteral calculi in octogenarians and nonagenarians: Contemporary in-hospital management—A joint study by the endourological section of the Austrian Association of Urology Drerup, Martin Özsoy, Mehmet Wehrberger, Clemens Lenz, Matthias Ramesmayer, Christian Stolzlechner, Philipp Zanier, Johannes Falkensammer, C. E. Handjev, Ivan Wasserscheid, Andreas Seklehner, Stephan PLoS One Research Article AIM: To assess contemporary in-hospital management of octogenarians and nonagenarians with ureteral calculi. MATERIALS AND METHODS: Review of patients aged ≥80 years hospitalized due to ureteral calculi. Data was extracted from eight Austrian centers of urology. Stone and patient related data were recorded. Treatment patterns in acute and elective settings were assessed. RESULTS: A total of 759 patients hospitalized with ureteral calculi were analyzed. Out of them, 643 were octogenarians (80-89years) and 116 nonagenarians (90–99 years). In an acute setting, simple de-obstruction with urinary diversions outnumbered active stone treatments like URS and SWL (62.6% vs. 26.9% vs. 10.5%). Decision making whether patients underwent active stone treatment was driven by stone location (OR = 0.28, p<0.0001), impaired renal function (OR = 0.28, p = 0.01) and indwelling urethral catheters (OR = 0.23, p = 0.01) but not by age or extend of mobility (all p>0.05). In elective settings, 81.5% of procedures were active stone treatments–mainly URS (76.9%), while DJ stent or nephrostomy replacements were noted in 14.2% and 4.3%. Octogenarians (OR = 14, p<0.0001) and patients capable of walking (OR = 4.51, p = 0.01) had significantly higher odds of receiving active stone. Stone free rates and complications rates with URS were similar between octogenarians and nonagenarians (p = 0.98 and p = 0.58). CONCLUSION: In acute settings, age and extend of mobility were not found to be independent predictors for active stone treatment. In elective settings, after having received urinary diversions, reduced mobility and nonagenarians were less likely to undergo stone removal treatments. Safety and efficacy of URS seems to be similar in octogenarians and nonagenarians. Public Library of Science 2023-01-17 /pmc/articles/PMC9844889/ /pubmed/36649250 http://dx.doi.org/10.1371/journal.pone.0280140 Text en © 2023 Drerup et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Drerup, Martin Özsoy, Mehmet Wehrberger, Clemens Lenz, Matthias Ramesmayer, Christian Stolzlechner, Philipp Zanier, Johannes Falkensammer, C. E. Handjev, Ivan Wasserscheid, Andreas Seklehner, Stephan Ureteral calculi in octogenarians and nonagenarians: Contemporary in-hospital management—A joint study by the endourological section of the Austrian Association of Urology |
title | Ureteral calculi in octogenarians and nonagenarians: Contemporary in-hospital management—A joint study by the endourological section of the Austrian Association of Urology |
title_full | Ureteral calculi in octogenarians and nonagenarians: Contemporary in-hospital management—A joint study by the endourological section of the Austrian Association of Urology |
title_fullStr | Ureteral calculi in octogenarians and nonagenarians: Contemporary in-hospital management—A joint study by the endourological section of the Austrian Association of Urology |
title_full_unstemmed | Ureteral calculi in octogenarians and nonagenarians: Contemporary in-hospital management—A joint study by the endourological section of the Austrian Association of Urology |
title_short | Ureteral calculi in octogenarians and nonagenarians: Contemporary in-hospital management—A joint study by the endourological section of the Austrian Association of Urology |
title_sort | ureteral calculi in octogenarians and nonagenarians: contemporary in-hospital management—a joint study by the endourological section of the austrian association of urology |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844889/ https://www.ncbi.nlm.nih.gov/pubmed/36649250 http://dx.doi.org/10.1371/journal.pone.0280140 |
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