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Ureteral calculi in octogenarians and nonagenarians: Contemporary in-hospital management—A joint study by the endourological section of the Austrian Association of Urology

AIM: To assess contemporary in-hospital management of octogenarians and nonagenarians with ureteral calculi. MATERIALS AND METHODS: Review of patients aged ≥80 years hospitalized due to ureteral calculi. Data was extracted from eight Austrian centers of urology. Stone and patient related data were r...

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Autores principales: Drerup, Martin, Özsoy, Mehmet, Wehrberger, Clemens, Lenz, Matthias, Ramesmayer, Christian, Stolzlechner, Philipp, Zanier, Johannes, Falkensammer, C. E., Handjev, Ivan, Wasserscheid, Andreas, Seklehner, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844889/
https://www.ncbi.nlm.nih.gov/pubmed/36649250
http://dx.doi.org/10.1371/journal.pone.0280140
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author Drerup, Martin
Özsoy, Mehmet
Wehrberger, Clemens
Lenz, Matthias
Ramesmayer, Christian
Stolzlechner, Philipp
Zanier, Johannes
Falkensammer, C. E.
Handjev, Ivan
Wasserscheid, Andreas
Seklehner, Stephan
author_facet Drerup, Martin
Özsoy, Mehmet
Wehrberger, Clemens
Lenz, Matthias
Ramesmayer, Christian
Stolzlechner, Philipp
Zanier, Johannes
Falkensammer, C. E.
Handjev, Ivan
Wasserscheid, Andreas
Seklehner, Stephan
author_sort Drerup, Martin
collection PubMed
description AIM: To assess contemporary in-hospital management of octogenarians and nonagenarians with ureteral calculi. MATERIALS AND METHODS: Review of patients aged ≥80 years hospitalized due to ureteral calculi. Data was extracted from eight Austrian centers of urology. Stone and patient related data were recorded. Treatment patterns in acute and elective settings were assessed. RESULTS: A total of 759 patients hospitalized with ureteral calculi were analyzed. Out of them, 643 were octogenarians (80-89years) and 116 nonagenarians (90–99 years). In an acute setting, simple de-obstruction with urinary diversions outnumbered active stone treatments like URS and SWL (62.6% vs. 26.9% vs. 10.5%). Decision making whether patients underwent active stone treatment was driven by stone location (OR = 0.28, p<0.0001), impaired renal function (OR = 0.28, p = 0.01) and indwelling urethral catheters (OR = 0.23, p = 0.01) but not by age or extend of mobility (all p>0.05). In elective settings, 81.5% of procedures were active stone treatments–mainly URS (76.9%), while DJ stent or nephrostomy replacements were noted in 14.2% and 4.3%. Octogenarians (OR = 14, p<0.0001) and patients capable of walking (OR = 4.51, p = 0.01) had significantly higher odds of receiving active stone. Stone free rates and complications rates with URS were similar between octogenarians and nonagenarians (p = 0.98 and p = 0.58). CONCLUSION: In acute settings, age and extend of mobility were not found to be independent predictors for active stone treatment. In elective settings, after having received urinary diversions, reduced mobility and nonagenarians were less likely to undergo stone removal treatments. Safety and efficacy of URS seems to be similar in octogenarians and nonagenarians.
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spelling pubmed-98448892023-01-18 Ureteral calculi in octogenarians and nonagenarians: Contemporary in-hospital management—A joint study by the endourological section of the Austrian Association of Urology Drerup, Martin Özsoy, Mehmet Wehrberger, Clemens Lenz, Matthias Ramesmayer, Christian Stolzlechner, Philipp Zanier, Johannes Falkensammer, C. E. Handjev, Ivan Wasserscheid, Andreas Seklehner, Stephan PLoS One Research Article AIM: To assess contemporary in-hospital management of octogenarians and nonagenarians with ureteral calculi. MATERIALS AND METHODS: Review of patients aged ≥80 years hospitalized due to ureteral calculi. Data was extracted from eight Austrian centers of urology. Stone and patient related data were recorded. Treatment patterns in acute and elective settings were assessed. RESULTS: A total of 759 patients hospitalized with ureteral calculi were analyzed. Out of them, 643 were octogenarians (80-89years) and 116 nonagenarians (90–99 years). In an acute setting, simple de-obstruction with urinary diversions outnumbered active stone treatments like URS and SWL (62.6% vs. 26.9% vs. 10.5%). Decision making whether patients underwent active stone treatment was driven by stone location (OR = 0.28, p<0.0001), impaired renal function (OR = 0.28, p = 0.01) and indwelling urethral catheters (OR = 0.23, p = 0.01) but not by age or extend of mobility (all p>0.05). In elective settings, 81.5% of procedures were active stone treatments–mainly URS (76.9%), while DJ stent or nephrostomy replacements were noted in 14.2% and 4.3%. Octogenarians (OR = 14, p<0.0001) and patients capable of walking (OR = 4.51, p = 0.01) had significantly higher odds of receiving active stone. Stone free rates and complications rates with URS were similar between octogenarians and nonagenarians (p = 0.98 and p = 0.58). CONCLUSION: In acute settings, age and extend of mobility were not found to be independent predictors for active stone treatment. In elective settings, after having received urinary diversions, reduced mobility and nonagenarians were less likely to undergo stone removal treatments. Safety and efficacy of URS seems to be similar in octogenarians and nonagenarians. Public Library of Science 2023-01-17 /pmc/articles/PMC9844889/ /pubmed/36649250 http://dx.doi.org/10.1371/journal.pone.0280140 Text en © 2023 Drerup et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Drerup, Martin
Özsoy, Mehmet
Wehrberger, Clemens
Lenz, Matthias
Ramesmayer, Christian
Stolzlechner, Philipp
Zanier, Johannes
Falkensammer, C. E.
Handjev, Ivan
Wasserscheid, Andreas
Seklehner, Stephan
Ureteral calculi in octogenarians and nonagenarians: Contemporary in-hospital management—A joint study by the endourological section of the Austrian Association of Urology
title Ureteral calculi in octogenarians and nonagenarians: Contemporary in-hospital management—A joint study by the endourological section of the Austrian Association of Urology
title_full Ureteral calculi in octogenarians and nonagenarians: Contemporary in-hospital management—A joint study by the endourological section of the Austrian Association of Urology
title_fullStr Ureteral calculi in octogenarians and nonagenarians: Contemporary in-hospital management—A joint study by the endourological section of the Austrian Association of Urology
title_full_unstemmed Ureteral calculi in octogenarians and nonagenarians: Contemporary in-hospital management—A joint study by the endourological section of the Austrian Association of Urology
title_short Ureteral calculi in octogenarians and nonagenarians: Contemporary in-hospital management—A joint study by the endourological section of the Austrian Association of Urology
title_sort ureteral calculi in octogenarians and nonagenarians: contemporary in-hospital management—a joint study by the endourological section of the austrian association of urology
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844889/
https://www.ncbi.nlm.nih.gov/pubmed/36649250
http://dx.doi.org/10.1371/journal.pone.0280140
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