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WTAP-mediated m(6)A modification modulates bone marrow mesenchymal stem cells differentiation potential and osteoporosis

An imbalance in the differentiation potential of bone marrow mesenchymal stem cells (BMSCs) is an important pathogenic mechanism underlying osteoporosis (OP). N6-methyladenosine (m(6)A) is the most common post-transcriptional modification in eukaryotic cells. The role of the Wilms’ tumor 1-associate...

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Detalles Bibliográficos
Autores principales: You, Yunhao, Liu, Jincheng, Zhang, Lu, Li, Xiang, Sun, Zhenqian, Dai, Zihan, Ma, Jinlong, Jiao, Guangjun, Chen, Yunzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845239/
https://www.ncbi.nlm.nih.gov/pubmed/36650131
http://dx.doi.org/10.1038/s41419-023-05565-x