Osteocyte Egln1/Phd2 links oxygen sensing and biomineralization via FGF23

Osteocytes act within a hypoxic environment to control key steps in bone formation. FGF23, a critical phosphate-regulating hormone, is stimulated by low oxygen/iron in acute and chronic diseases, however the molecular mechanisms directing this process remain unclear. Our goal was to identify the ost...

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Detalles Bibliográficos
Autores principales: Noonan, Megan L., Ni, Pu, Solis, Emmanuel, Marambio, Yamil G., Agoro, Rafiou, Chu, Xiaona, Wang, Yue, Gao, Hongyu, Xuei, Xiaoling, Clinkenbeard, Erica L., Jiang, Guanglong, Liu, Sheng, Stegen, Steve, Carmeliet, Geert, Thompson, William R., Liu, Yunlong, Wan, Jun, White, Kenneth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845350/
https://www.ncbi.nlm.nih.gov/pubmed/36650133
http://dx.doi.org/10.1038/s41413-022-00241-w

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