Cargando…

Intracranial Rosai-Dorfman Disease: A Case to Remember

Sinus histiocytosis with massive lymphadenopathy (SHML), an alternative term for Rosai-Dorfman disease (RDD), is a rare benign idiopathic immune-related lymphoproliferative condition. The central nervous system (CNS) has been documented to be involved in RDD, although lymph nodes are the organs that...

Descripción completa

Detalles Bibliográficos
Autores principales: Unadkat, Bhavik S, Kashikar, Shivali V, Bhansali, Pratik J, Shetty, Neha D, Shelar, Sheetal S, Suryadevara, Manasa, Dharmadhikari, Abhijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845528/
https://www.ncbi.nlm.nih.gov/pubmed/36660540
http://dx.doi.org/10.7759/cureus.32605
_version_ 1784870920725200896
author Unadkat, Bhavik S
Kashikar, Shivali V
Bhansali, Pratik J
Shetty, Neha D
Shelar, Sheetal S
Suryadevara, Manasa
Dharmadhikari, Abhijay
author_facet Unadkat, Bhavik S
Kashikar, Shivali V
Bhansali, Pratik J
Shetty, Neha D
Shelar, Sheetal S
Suryadevara, Manasa
Dharmadhikari, Abhijay
author_sort Unadkat, Bhavik S
collection PubMed
description Sinus histiocytosis with massive lymphadenopathy (SHML), an alternative term for Rosai-Dorfman disease (RDD), is a rare benign idiopathic immune-related lymphoproliferative condition. The central nervous system (CNS) has been documented to be involved in RDD, although lymph nodes are the organs that are most frequently and primarily associated with the disease manifestation. Nonetheless, CNS involvement in RDD is rare and poorly understood. As a result, there is a lack of a solid basis for therapeutic approaches for CNS involvement in RDD. Here, we present a case of RDD with cerebral involvement, a rare presentation of RDD with atypical symptoms. A brief assessment of the radiographic appearance, histological findings, and the peculiar manifestations of the disease is provided.
format Online
Article
Text
id pubmed-9845528
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-98455282023-01-18 Intracranial Rosai-Dorfman Disease: A Case to Remember Unadkat, Bhavik S Kashikar, Shivali V Bhansali, Pratik J Shetty, Neha D Shelar, Sheetal S Suryadevara, Manasa Dharmadhikari, Abhijay Cureus Radiology Sinus histiocytosis with massive lymphadenopathy (SHML), an alternative term for Rosai-Dorfman disease (RDD), is a rare benign idiopathic immune-related lymphoproliferative condition. The central nervous system (CNS) has been documented to be involved in RDD, although lymph nodes are the organs that are most frequently and primarily associated with the disease manifestation. Nonetheless, CNS involvement in RDD is rare and poorly understood. As a result, there is a lack of a solid basis for therapeutic approaches for CNS involvement in RDD. Here, we present a case of RDD with cerebral involvement, a rare presentation of RDD with atypical symptoms. A brief assessment of the radiographic appearance, histological findings, and the peculiar manifestations of the disease is provided. Cureus 2022-12-16 /pmc/articles/PMC9845528/ /pubmed/36660540 http://dx.doi.org/10.7759/cureus.32605 Text en Copyright © 2022, Unadkat et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Radiology
Unadkat, Bhavik S
Kashikar, Shivali V
Bhansali, Pratik J
Shetty, Neha D
Shelar, Sheetal S
Suryadevara, Manasa
Dharmadhikari, Abhijay
Intracranial Rosai-Dorfman Disease: A Case to Remember
title Intracranial Rosai-Dorfman Disease: A Case to Remember
title_full Intracranial Rosai-Dorfman Disease: A Case to Remember
title_fullStr Intracranial Rosai-Dorfman Disease: A Case to Remember
title_full_unstemmed Intracranial Rosai-Dorfman Disease: A Case to Remember
title_short Intracranial Rosai-Dorfman Disease: A Case to Remember
title_sort intracranial rosai-dorfman disease: a case to remember
topic Radiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845528/
https://www.ncbi.nlm.nih.gov/pubmed/36660540
http://dx.doi.org/10.7759/cureus.32605
work_keys_str_mv AT unadkatbhaviks intracranialrosaidorfmandiseaseacasetoremember
AT kashikarshivaliv intracranialrosaidorfmandiseaseacasetoremember
AT bhansalipratikj intracranialrosaidorfmandiseaseacasetoremember
AT shettynehad intracranialrosaidorfmandiseaseacasetoremember
AT shelarsheetals intracranialrosaidorfmandiseaseacasetoremember
AT suryadevaramanasa intracranialrosaidorfmandiseaseacasetoremember
AT dharmadhikariabhijay intracranialrosaidorfmandiseaseacasetoremember