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Intracranial Rosai-Dorfman Disease: A Case to Remember
Sinus histiocytosis with massive lymphadenopathy (SHML), an alternative term for Rosai-Dorfman disease (RDD), is a rare benign idiopathic immune-related lymphoproliferative condition. The central nervous system (CNS) has been documented to be involved in RDD, although lymph nodes are the organs that...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845528/ https://www.ncbi.nlm.nih.gov/pubmed/36660540 http://dx.doi.org/10.7759/cureus.32605 |
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author | Unadkat, Bhavik S Kashikar, Shivali V Bhansali, Pratik J Shetty, Neha D Shelar, Sheetal S Suryadevara, Manasa Dharmadhikari, Abhijay |
author_facet | Unadkat, Bhavik S Kashikar, Shivali V Bhansali, Pratik J Shetty, Neha D Shelar, Sheetal S Suryadevara, Manasa Dharmadhikari, Abhijay |
author_sort | Unadkat, Bhavik S |
collection | PubMed |
description | Sinus histiocytosis with massive lymphadenopathy (SHML), an alternative term for Rosai-Dorfman disease (RDD), is a rare benign idiopathic immune-related lymphoproliferative condition. The central nervous system (CNS) has been documented to be involved in RDD, although lymph nodes are the organs that are most frequently and primarily associated with the disease manifestation. Nonetheless, CNS involvement in RDD is rare and poorly understood. As a result, there is a lack of a solid basis for therapeutic approaches for CNS involvement in RDD. Here, we present a case of RDD with cerebral involvement, a rare presentation of RDD with atypical symptoms. A brief assessment of the radiographic appearance, histological findings, and the peculiar manifestations of the disease is provided. |
format | Online Article Text |
id | pubmed-9845528 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-98455282023-01-18 Intracranial Rosai-Dorfman Disease: A Case to Remember Unadkat, Bhavik S Kashikar, Shivali V Bhansali, Pratik J Shetty, Neha D Shelar, Sheetal S Suryadevara, Manasa Dharmadhikari, Abhijay Cureus Radiology Sinus histiocytosis with massive lymphadenopathy (SHML), an alternative term for Rosai-Dorfman disease (RDD), is a rare benign idiopathic immune-related lymphoproliferative condition. The central nervous system (CNS) has been documented to be involved in RDD, although lymph nodes are the organs that are most frequently and primarily associated with the disease manifestation. Nonetheless, CNS involvement in RDD is rare and poorly understood. As a result, there is a lack of a solid basis for therapeutic approaches for CNS involvement in RDD. Here, we present a case of RDD with cerebral involvement, a rare presentation of RDD with atypical symptoms. A brief assessment of the radiographic appearance, histological findings, and the peculiar manifestations of the disease is provided. Cureus 2022-12-16 /pmc/articles/PMC9845528/ /pubmed/36660540 http://dx.doi.org/10.7759/cureus.32605 Text en Copyright © 2022, Unadkat et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Radiology Unadkat, Bhavik S Kashikar, Shivali V Bhansali, Pratik J Shetty, Neha D Shelar, Sheetal S Suryadevara, Manasa Dharmadhikari, Abhijay Intracranial Rosai-Dorfman Disease: A Case to Remember |
title | Intracranial Rosai-Dorfman Disease: A Case to Remember |
title_full | Intracranial Rosai-Dorfman Disease: A Case to Remember |
title_fullStr | Intracranial Rosai-Dorfman Disease: A Case to Remember |
title_full_unstemmed | Intracranial Rosai-Dorfman Disease: A Case to Remember |
title_short | Intracranial Rosai-Dorfman Disease: A Case to Remember |
title_sort | intracranial rosai-dorfman disease: a case to remember |
topic | Radiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845528/ https://www.ncbi.nlm.nih.gov/pubmed/36660540 http://dx.doi.org/10.7759/cureus.32605 |
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