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Research progress of natural silk fibroin and the application for drug delivery in chemotherapies
Silk fibroin has been widely used in biological fields due to its biocompatibility, mechanical properties, biodegradability, and safety. Recently, silk fibroin as a drug carrier was developed rapidly and achieved remarkable progress in cancer treatment. The silk fibroin-based delivery system could e...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845586/ https://www.ncbi.nlm.nih.gov/pubmed/36686706 http://dx.doi.org/10.3389/fphar.2022.1071868 |
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author | Yu, Bin Li, Yanli Lin, Yuxian Zhu, Yuanying Hao, Teng Wu, Yan Sun, Zheng Yang, Xin Xu, Hui |
author_facet | Yu, Bin Li, Yanli Lin, Yuxian Zhu, Yuanying Hao, Teng Wu, Yan Sun, Zheng Yang, Xin Xu, Hui |
author_sort | Yu, Bin |
collection | PubMed |
description | Silk fibroin has been widely used in biological fields due to its biocompatibility, mechanical properties, biodegradability, and safety. Recently, silk fibroin as a drug carrier was developed rapidly and achieved remarkable progress in cancer treatment. The silk fibroin-based delivery system could effectively kill tumor cells without significant side effects and drug resistance. However, few studies have been reported on silk fibroin delivery systems for antitumor therapy. The advancement of silk fibroin-based drug delivery systems research and its applications in cancer therapy are highlighted in this study. The properties, applications, private opinions, and future prospects of silk fibroin carriers are discussed to understand better the development of anti-cancer drug delivery systems, which may also contribute to advancing silk fibroin innovation. |
format | Online Article Text |
id | pubmed-9845586 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-98455862023-01-19 Research progress of natural silk fibroin and the application for drug delivery in chemotherapies Yu, Bin Li, Yanli Lin, Yuxian Zhu, Yuanying Hao, Teng Wu, Yan Sun, Zheng Yang, Xin Xu, Hui Front Pharmacol Pharmacology Silk fibroin has been widely used in biological fields due to its biocompatibility, mechanical properties, biodegradability, and safety. Recently, silk fibroin as a drug carrier was developed rapidly and achieved remarkable progress in cancer treatment. The silk fibroin-based delivery system could effectively kill tumor cells without significant side effects and drug resistance. However, few studies have been reported on silk fibroin delivery systems for antitumor therapy. The advancement of silk fibroin-based drug delivery systems research and its applications in cancer therapy are highlighted in this study. The properties, applications, private opinions, and future prospects of silk fibroin carriers are discussed to understand better the development of anti-cancer drug delivery systems, which may also contribute to advancing silk fibroin innovation. Frontiers Media S.A. 2023-01-04 /pmc/articles/PMC9845586/ /pubmed/36686706 http://dx.doi.org/10.3389/fphar.2022.1071868 Text en Copyright © 2023 Yu, Li, Lin, Zhu, Hao, Wu, Sun, Yang and Xu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pharmacology Yu, Bin Li, Yanli Lin, Yuxian Zhu, Yuanying Hao, Teng Wu, Yan Sun, Zheng Yang, Xin Xu, Hui Research progress of natural silk fibroin and the application for drug delivery in chemotherapies |
title | Research progress of natural silk fibroin and the application for drug delivery in chemotherapies |
title_full | Research progress of natural silk fibroin and the application for drug delivery in chemotherapies |
title_fullStr | Research progress of natural silk fibroin and the application for drug delivery in chemotherapies |
title_full_unstemmed | Research progress of natural silk fibroin and the application for drug delivery in chemotherapies |
title_short | Research progress of natural silk fibroin and the application for drug delivery in chemotherapies |
title_sort | research progress of natural silk fibroin and the application for drug delivery in chemotherapies |
topic | Pharmacology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845586/ https://www.ncbi.nlm.nih.gov/pubmed/36686706 http://dx.doi.org/10.3389/fphar.2022.1071868 |
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