Cargando…

Research progress of natural silk fibroin and the application for drug delivery in chemotherapies

Silk fibroin has been widely used in biological fields due to its biocompatibility, mechanical properties, biodegradability, and safety. Recently, silk fibroin as a drug carrier was developed rapidly and achieved remarkable progress in cancer treatment. The silk fibroin-based delivery system could e...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Bin, Li, Yanli, Lin, Yuxian, Zhu, Yuanying, Hao, Teng, Wu, Yan, Sun, Zheng, Yang, Xin, Xu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845586/
https://www.ncbi.nlm.nih.gov/pubmed/36686706
http://dx.doi.org/10.3389/fphar.2022.1071868
_version_ 1784870935036166144
author Yu, Bin
Li, Yanli
Lin, Yuxian
Zhu, Yuanying
Hao, Teng
Wu, Yan
Sun, Zheng
Yang, Xin
Xu, Hui
author_facet Yu, Bin
Li, Yanli
Lin, Yuxian
Zhu, Yuanying
Hao, Teng
Wu, Yan
Sun, Zheng
Yang, Xin
Xu, Hui
author_sort Yu, Bin
collection PubMed
description Silk fibroin has been widely used in biological fields due to its biocompatibility, mechanical properties, biodegradability, and safety. Recently, silk fibroin as a drug carrier was developed rapidly and achieved remarkable progress in cancer treatment. The silk fibroin-based delivery system could effectively kill tumor cells without significant side effects and drug resistance. However, few studies have been reported on silk fibroin delivery systems for antitumor therapy. The advancement of silk fibroin-based drug delivery systems research and its applications in cancer therapy are highlighted in this study. The properties, applications, private opinions, and future prospects of silk fibroin carriers are discussed to understand better the development of anti-cancer drug delivery systems, which may also contribute to advancing silk fibroin innovation.
format Online
Article
Text
id pubmed-9845586
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-98455862023-01-19 Research progress of natural silk fibroin and the application for drug delivery in chemotherapies Yu, Bin Li, Yanli Lin, Yuxian Zhu, Yuanying Hao, Teng Wu, Yan Sun, Zheng Yang, Xin Xu, Hui Front Pharmacol Pharmacology Silk fibroin has been widely used in biological fields due to its biocompatibility, mechanical properties, biodegradability, and safety. Recently, silk fibroin as a drug carrier was developed rapidly and achieved remarkable progress in cancer treatment. The silk fibroin-based delivery system could effectively kill tumor cells without significant side effects and drug resistance. However, few studies have been reported on silk fibroin delivery systems for antitumor therapy. The advancement of silk fibroin-based drug delivery systems research and its applications in cancer therapy are highlighted in this study. The properties, applications, private opinions, and future prospects of silk fibroin carriers are discussed to understand better the development of anti-cancer drug delivery systems, which may also contribute to advancing silk fibroin innovation. Frontiers Media S.A. 2023-01-04 /pmc/articles/PMC9845586/ /pubmed/36686706 http://dx.doi.org/10.3389/fphar.2022.1071868 Text en Copyright © 2023 Yu, Li, Lin, Zhu, Hao, Wu, Sun, Yang and Xu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Yu, Bin
Li, Yanli
Lin, Yuxian
Zhu, Yuanying
Hao, Teng
Wu, Yan
Sun, Zheng
Yang, Xin
Xu, Hui
Research progress of natural silk fibroin and the application for drug delivery in chemotherapies
title Research progress of natural silk fibroin and the application for drug delivery in chemotherapies
title_full Research progress of natural silk fibroin and the application for drug delivery in chemotherapies
title_fullStr Research progress of natural silk fibroin and the application for drug delivery in chemotherapies
title_full_unstemmed Research progress of natural silk fibroin and the application for drug delivery in chemotherapies
title_short Research progress of natural silk fibroin and the application for drug delivery in chemotherapies
title_sort research progress of natural silk fibroin and the application for drug delivery in chemotherapies
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845586/
https://www.ncbi.nlm.nih.gov/pubmed/36686706
http://dx.doi.org/10.3389/fphar.2022.1071868
work_keys_str_mv AT yubin researchprogressofnaturalsilkfibroinandtheapplicationfordrugdeliveryinchemotherapies
AT liyanli researchprogressofnaturalsilkfibroinandtheapplicationfordrugdeliveryinchemotherapies
AT linyuxian researchprogressofnaturalsilkfibroinandtheapplicationfordrugdeliveryinchemotherapies
AT zhuyuanying researchprogressofnaturalsilkfibroinandtheapplicationfordrugdeliveryinchemotherapies
AT haoteng researchprogressofnaturalsilkfibroinandtheapplicationfordrugdeliveryinchemotherapies
AT wuyan researchprogressofnaturalsilkfibroinandtheapplicationfordrugdeliveryinchemotherapies
AT sunzheng researchprogressofnaturalsilkfibroinandtheapplicationfordrugdeliveryinchemotherapies
AT yangxin researchprogressofnaturalsilkfibroinandtheapplicationfordrugdeliveryinchemotherapies
AT xuhui researchprogressofnaturalsilkfibroinandtheapplicationfordrugdeliveryinchemotherapies