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The power of the smallest: The inhibitory activity of microbial volatile organic compounds against phytopathogens

Plant diseases caused by phytopathogens result in huge economic losses in agriculture. In addition, the use of chemical products to control such diseases causes many problems to the environment and to human health. However, some bacteria and fungi have a mutualistic relationship with plants in natur...

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Autores principales: Almeida, Octávio Augusto Costa, de Araujo, Natália Oliveira, Dias, Bruno Henrique Silva, de Sant’Anna Freitas, Carla, Coerini, Luciane Fender, Ryu, Choong-Min, de Castro Oliveira, Juliana Velasco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845590/
https://www.ncbi.nlm.nih.gov/pubmed/36687575
http://dx.doi.org/10.3389/fmicb.2022.951130
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author Almeida, Octávio Augusto Costa
de Araujo, Natália Oliveira
Dias, Bruno Henrique Silva
de Sant’Anna Freitas, Carla
Coerini, Luciane Fender
Ryu, Choong-Min
de Castro Oliveira, Juliana Velasco
author_facet Almeida, Octávio Augusto Costa
de Araujo, Natália Oliveira
Dias, Bruno Henrique Silva
de Sant’Anna Freitas, Carla
Coerini, Luciane Fender
Ryu, Choong-Min
de Castro Oliveira, Juliana Velasco
author_sort Almeida, Octávio Augusto Costa
collection PubMed
description Plant diseases caused by phytopathogens result in huge economic losses in agriculture. In addition, the use of chemical products to control such diseases causes many problems to the environment and to human health. However, some bacteria and fungi have a mutualistic relationship with plants in nature, mainly exchanging nutrients and protection. Thus, exploring those beneficial microorganisms has been an interesting and promising alternative for mitigating the use of agrochemicals and, consequently, achieving a more sustainable agriculture. Microorganisms are able to produce and excrete several metabolites, but volatile organic compounds (VOCs) have huge biotechnology potential. Microbial VOCs are small molecules from different chemical classes, such as alkenes, alcohols, ketones, organic acids, terpenes, benzenoids and pyrazines. Interestingly, volatilomes are species-specific and also change according to microbial growth conditions. The interaction of VOCs with other organisms, such as plants, insects, and other bacteria and fungi, can cause a wide range of effects. In this review, we show that a large variety of plant pathogens are inhibited by microbial VOCs with a focus on the in vitro and in vivo inhibition of phytopathogens of greater scientific and economic importance in agriculture, such as Ralstonia solanacearum, Botrytis cinerea, Xanthomonas and Fusarium species. In this scenario, some genera of VOC-producing microorganisms stand out as antagonists, including Bacillus, Pseudomonas, Serratia and Streptomyces. We also highlight the known molecular and physiological mechanisms by which VOCs inhibit the growth of phytopathogens. Microbial VOCs can provoke many changes in these microorganisms, such as vacuolization, fungal hyphal rupture, loss of intracellular components, regulation of metabolism and pathogenicity genes, plus the expression of proteins important in the host response. Furthermore, we demonstrate that there are aspects to investigate by discussing questions that are still not very clear in this research area, especially those that are essential for the future use of such beneficial microorganisms as biocontrol products in field crops. Therefore, we bring to light the great biotechnological potential of VOCs to help make agriculture more sustainable.
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spelling pubmed-98455902023-01-19 The power of the smallest: The inhibitory activity of microbial volatile organic compounds against phytopathogens Almeida, Octávio Augusto Costa de Araujo, Natália Oliveira Dias, Bruno Henrique Silva de Sant’Anna Freitas, Carla Coerini, Luciane Fender Ryu, Choong-Min de Castro Oliveira, Juliana Velasco Front Microbiol Microbiology Plant diseases caused by phytopathogens result in huge economic losses in agriculture. In addition, the use of chemical products to control such diseases causes many problems to the environment and to human health. However, some bacteria and fungi have a mutualistic relationship with plants in nature, mainly exchanging nutrients and protection. Thus, exploring those beneficial microorganisms has been an interesting and promising alternative for mitigating the use of agrochemicals and, consequently, achieving a more sustainable agriculture. Microorganisms are able to produce and excrete several metabolites, but volatile organic compounds (VOCs) have huge biotechnology potential. Microbial VOCs are small molecules from different chemical classes, such as alkenes, alcohols, ketones, organic acids, terpenes, benzenoids and pyrazines. Interestingly, volatilomes are species-specific and also change according to microbial growth conditions. The interaction of VOCs with other organisms, such as plants, insects, and other bacteria and fungi, can cause a wide range of effects. In this review, we show that a large variety of plant pathogens are inhibited by microbial VOCs with a focus on the in vitro and in vivo inhibition of phytopathogens of greater scientific and economic importance in agriculture, such as Ralstonia solanacearum, Botrytis cinerea, Xanthomonas and Fusarium species. In this scenario, some genera of VOC-producing microorganisms stand out as antagonists, including Bacillus, Pseudomonas, Serratia and Streptomyces. We also highlight the known molecular and physiological mechanisms by which VOCs inhibit the growth of phytopathogens. Microbial VOCs can provoke many changes in these microorganisms, such as vacuolization, fungal hyphal rupture, loss of intracellular components, regulation of metabolism and pathogenicity genes, plus the expression of proteins important in the host response. Furthermore, we demonstrate that there are aspects to investigate by discussing questions that are still not very clear in this research area, especially those that are essential for the future use of such beneficial microorganisms as biocontrol products in field crops. Therefore, we bring to light the great biotechnological potential of VOCs to help make agriculture more sustainable. Frontiers Media S.A. 2023-01-04 /pmc/articles/PMC9845590/ /pubmed/36687575 http://dx.doi.org/10.3389/fmicb.2022.951130 Text en Copyright © 2022 Almeida, de Araujo, Dias, de Sant’Anna Freitas, Coerini, Ryu and de Castro Oliveira. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Almeida, Octávio Augusto Costa
de Araujo, Natália Oliveira
Dias, Bruno Henrique Silva
de Sant’Anna Freitas, Carla
Coerini, Luciane Fender
Ryu, Choong-Min
de Castro Oliveira, Juliana Velasco
The power of the smallest: The inhibitory activity of microbial volatile organic compounds against phytopathogens
title The power of the smallest: The inhibitory activity of microbial volatile organic compounds against phytopathogens
title_full The power of the smallest: The inhibitory activity of microbial volatile organic compounds against phytopathogens
title_fullStr The power of the smallest: The inhibitory activity of microbial volatile organic compounds against phytopathogens
title_full_unstemmed The power of the smallest: The inhibitory activity of microbial volatile organic compounds against phytopathogens
title_short The power of the smallest: The inhibitory activity of microbial volatile organic compounds against phytopathogens
title_sort power of the smallest: the inhibitory activity of microbial volatile organic compounds against phytopathogens
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845590/
https://www.ncbi.nlm.nih.gov/pubmed/36687575
http://dx.doi.org/10.3389/fmicb.2022.951130
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