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Arenobufagin causes ferroptosis in human gastric cancer cells by increasing rev-erbα expression

BACKGROUND AND AIMS: Gastric cancer is the fifth most diagnosed malignant tumor worldwide with limited effective chemotherapy. Ferroptosis is a new type of programmed cell death, which is becoming as a novel therapeutic target for tumors. Arenobufagin (ArBu) is a bufadienolide isolated from toad ski...

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Detalles Bibliográficos
Autores principales: Chen, Ke, Li, Angling, Wang, Jian, Li, Dongchang, Wang, Xiaoshan, Liu, Chengwei, Wang, Zhengguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845647/
https://www.ncbi.nlm.nih.gov/pubmed/36685074
http://dx.doi.org/10.1016/j.jtcme.2022.10.007