Cargando…
Zika virus cleaves GSDMD to disseminate prognosticable and controllable oncolysis in a human glioblastoma cell model
Glioblastoma (GBM) is the most common aggressive malignant brain cancer and is chemo- and radioresistant, with poor therapeutic outcomes. The “double-edged sword” of virus-induced cell death could be a potential solution if the oncolytic virus specifically kills cancer cells but spares normal ones....
Autores principales: | Kao, Yu-Ting, Wang, Hsin-I, Shie, Chi-Ting, Lin, Chiou-Feng, Lai, Michael M.C., Yu, Chia-Yi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845690/ https://www.ncbi.nlm.nih.gov/pubmed/36699618 http://dx.doi.org/10.1016/j.omto.2022.12.008 |
Ejemplares similares
-
Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD
por: Heilig, Rosalie, et al.
Publicado: (2020) -
Secoisolariciresinol diglucoside induces pyroptosis by activating caspase‐1 to cleave GSDMD in colorectal cancer cells
por: Chen, Tuo, et al.
Publicado: (2022) -
Combination of Oncolytic Measles Virus and Ursolic Acid Synergistically Induces Oncolysis of Hepatocellular Carcinoma Cells
por: Liu, Ching-Hsuan, et al.
Publicado: (2023) -
Dichloroacetate blocks aerobic glycolytic adaptation to attenuated measles virus and promotes viral replication leading to enhanced oncolysis in glioblastoma
por: Li, Chunyan, et al.
Publicado: (2014) -
Immunological Aspects of Viral Oncolysis
por: Stim, Thomas B.
Publicado: (1967)