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RSK1 and RSK2 serine/threonine kinases regulate different transcription programs in cancer

The 90 kDa ribosomal S6 kinases (RSKs) are serine threonine kinases comprising four isoforms. The isoforms can have overlapping functions in regulation of migration, invasion, proliferation, survival, and transcription in various cancer types. However, isoform specific differences in RSK1 versus RSK...

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Detalles Bibliográficos
Autores principales: Yang, Won Seok, Caliva, Maisel J., Khadka, Vedbar S., Tiirikainen, Maarit, Matter, Michelle L., Deng, Youping, Ramos, Joe W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845784/
https://www.ncbi.nlm.nih.gov/pubmed/36684450
http://dx.doi.org/10.3389/fcell.2022.1015665