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Functional changes in cytotoxic CD8+ T-cell cross-reactivity against the SARS-CoV-2 Omicron variant after mRNA vaccination

Understanding the T-cell responses involved in inhibiting COVID-19 severity is crucial for developing new therapeutic and vaccine strategies. Here, we characterized SARS-CoV-2 spike-specific CD8(+) T cells in vaccinees longitudinally. The BNT162b2 mRNA vaccine can induce spike-specific CD8(+) T cell...

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Detalles Bibliográficos
Autores principales:	Nogimori, Takuto, Suzuki, Koichiro, Masuta, Yuji, Washizaki, Ayaka, Yagoto, Mika, Ikeda, Mami, Katayama, Yuki, Kanda, Hidenori, Takada, Minoru, Minami, Shohei, Kobayashi, Takeshi, Takahama, Shokichi, Yoshioka, Yasuo, Yamamoto, Takuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845949/ https://www.ncbi.nlm.nih.gov/pubmed/36685601 http://dx.doi.org/10.3389/fimmu.2022.1081047

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