MEX3A Mediates p53 Degradation to Suppress Ferroptosis and Facilitate Ovarian Cancer Tumorigenesis

Epithelial ovarian cancer is a highly heterogeneous and malignant female cancer with an overall low survival rate. Mutations in p53 are prevalent in the major ovarian cancer histotype, high-grade serous ovarian carcinoma (HGSOC), while p53 mutations are much less frequent in other ovarian cancer sub...

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Detalles Bibliográficos
Autores principales: Wang, Cheng-Kai, Chen, Tzu-Jou, Tan, Grace Y.T., Chang, Fang-Pei, Sridharan, Samyuktha, Yu, Chen-Hsin Albert, Chang, Yen-Hou, Chen, Yi-Jen, Cheng, Li-Tzu, Hwang-Verslues, Wendy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Molecular Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9845988/
https://www.ncbi.nlm.nih.gov/pubmed/36354374
http://dx.doi.org/10.1158/0008-5472.CAN-22-1159

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