Protocol to analyze and validate transcriptomic changes in PDGFRβ-KO mesenchymal stem cell osteogenic potential in the mouse embryo

Mesenchymal stem/stromal cells (MSCs) can differentiate into osteoblasts under appropriate conditions. PDGFRβ signaling controls MSC osteogenic potential both transcriptomically and in culture. Here, we present a “computer to the bench” protocol to analyze changes in MSC osteogenic potential at tran...

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Detalles Bibliográficos
Autores principales: Kilpatrick, Alastair Morris, Marques, Madalena, Gomez-Salazar, Mario, Stefancova, Dorota, Sá da Bandeira, Diana, Crisan, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846014/
https://www.ncbi.nlm.nih.gov/pubmed/36640365
http://dx.doi.org/10.1016/j.xpro.2022.102016

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